Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 18/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20225268 | 0.88 | PDK2 (0.47) | PDK2 | |
| SCHEMBL20225266 | 0.88 | PDK2 (0.47) | PDK2 | |
| SCHEMBL19863933 | 0.82 | PDK2 (0.42) | PDK2 | |
| SCHEMBL17533937 | 0.82 | PDK2 (0.48) | PDK2 | |
| SCHEMBL19869583 | 0.82 | PDK2 (0.38) | PDK2 | |
| SCHEMBL20845173 | 0.81 | PDK2 (0.38) | PDK2 | |
| SCHEMBL20845364 | 0.81 | PDK2 (0.38) | PDK2 | |
| SCHEMBL19846172 | 0.80 | PDK2 (0.44) | PDK2 | |
| SCHEMBL431255 | 0.79 | PDK2 (0.49) | PDK2 | |
| SCHEMBL30631789 | 0.79 | PDK2 (0.49) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10693075-B2 | Spiro compound and organic electronic device comprising the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2020-06-23 | — | — | US | disclosed |
| US-20180047907-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2018-02-15 | — | — | US | disclosed |
| US-20180047907-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10693075-B2 | Spiro compound and organic electronic device comprising the same | ESRRA, REN, ESRRB | PDK2 1145/4885 |
| US-20180047907-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | CNKSR1, CBX4, RBX1 | PDK2 2859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.