Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 2/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26293318 | 1.00 | DPP4 (0.39) | DPP4DPP8MAPTKCNN4CYP1A2 | |
| SCHEMBL19871025 | 0.82 | CTSC (0.38) | DPP4DPP8MAPTCYP1A2CYP2D6 | |
| SCHEMBL12038615 | 0.80 | APAF1 (0.42) | MAPTKCNN4CYP1A2CYP2D6GRIN2D | |
| SCHEMBL26292979 | 0.80 | APAF1 (0.42) | MAPTKCNN4CYP1A2CYP2D6GRIN2D | |
| SCHEMBL16743931 | 0.78 | MAPT (0.41) | MAPTKCNN4CYP1A2CYP2D6GRIN2D | |
| SCHEMBL31037702 | 0.77 | MAPT (0.40) | DPP4DPP8MAPTKCNN4CYP1A2 | |
| SCHEMBL26294139 | 0.77 | MAPT (0.43) | MAPTKCNN4CYP1A2CYP2D6GRIN2D | |
| SCHEMBL26294391 | 0.77 | MAPT (0.40) | MAPTKCNN4CYP1A2CYP2D6GRIN2D | |
| SCHEMBL26294014 | 0.77 | MAPT (0.43) | MAPTKCNN4CYP1A2CYP2D6GRIN2D | |
| SCHEMBL19871023 | 0.77 | MAPT (0.40) | MAPTKCNN4CYP1A2CYP2D6GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180044303-A1 | 1,2,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE ONCOLOGY LIMITED (IN) | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044303-A1 | 1,2,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | PDCD1, PDCD1LG2, CD274 | DPP4 1989/4885DPP8 2206/4885MAPT 4206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.