Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12038615 | 0.81 | APAF1 (0.42) | MAPTRAB9AALDH1A1KCNN4CYP1A2 | |
| SCHEMBL26292979 | 0.81 | APAF1 (0.42) | MAPTRAB9AALDH1A1KCNN4CYP1A2 | |
| SCHEMBL16743931 | 0.79 | MAPT (0.41) | MAPTALDH1A1KCNN4CYP1A2CYP2D6 | |
| SCHEMBL28776911 | 0.79 | MAPT (0.35) | MAPTPOLBKCNN4CYP1A2LMNA | |
| SCHEMBL26294014 | 0.78 | MAPT (0.43) | MAPTKCNN4CYP1A2CYP2D6LMNA | |
| SCHEMBL26294391 | 0.78 | MAPT (0.40) | MAPTKCNN4CYP1A2CYP2D6LMNA | |
| SCHEMBL26294139 | 0.78 | MAPT (0.43) | MAPTKCNN4CYP1A2CYP2D6LMNA | |
| SCHEMBL19871023 | 0.78 | MAPT (0.40) | MAPTKCNN4CYP1A2CYP2D6LMNA | |
| SCHEMBL15249334 | 0.77 | ESRRB (0.47) | MAPTALDH1A1KCNN4CYP1A2CYP3A4 | |
| SCHEMBL19871024 | 0.77 | DPP4 (0.39) | MAPTDPP4DPP8KCNN4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658667-A1 | CYCLIC PEPTIDES FOR INHIBITING TNF RECEPTOR 1 ACTIVITY | Merck Sharp & Dohme LLC (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163691-A1 | CYCLIC PEPTIDES FOR INHIBITING TNF RECEPTOR 1 ACTIVITY | MERCK SHARP & DOHME LLC (US) | 2024-08-08 | — | — | WO | disclosed |