Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.40 |
| ▸ | HRH2 | P25021 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16928030 | 0.94 | CHRM3 (0.42) | ACP1HRH2HRH1HRH3CAMK2D | |
| SCHEMBL16928032 | 0.92 | CAMK2D (0.44) | ACP1HRH2HRH1HRH3CAMK2D | |
| SCHEMBL16928575 | 0.92 | KDM1A (0.45) | ACP1HRH2HRH1HRH3CAMK2D | |
| SCHEMBL16928309 | 0.91 | ACP1 (0.47) | ACP1HRH2HRH1HRH3CAMK2D | |
| SCHEMBL16928348 | 0.91 | CHRM3 (0.39) | ACP1HRH2HRH1HRH3CAMK2D | |
| SCHEMBL16928011 | 0.91 | ACP1 (0.48) | ACP1HRH2HRH1HRH3CAMK2D | |
| SCHEMBL17721591 | 0.90 | ACP1 (0.39) | ACP1HRH2HRH1HRH3CAMK2D | |
| SCHEMBL17721587 | 0.89 | ACP1 (0.38) | ACP1HRH2HRH1HRH3CAMK2D | |
| SCHEMBL19873479 | 0.88 | ACP1 (0.45) | ACP1HRH2HRH1HRH3CAMK2D | |
| SCHEMBL17721574 | 0.88 | PTGS2 (0.39) | ACP1HRH2HRH1HRH3CAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351538-A1 | TRIAZINE COMPOUNDS AND COMPOSITIONS THEREOF AND METHODS FOR TREATING MALARIA AND CHEMOPROPHYLAXIS | The United States of America, as represented by The Secretary of The Army, on behalf of Walter Reed Army Institute of Research (US) | 2018-07-25 | — | — | EP | disclosed |
| EP-2970153-B1 | TRIAZINE COMPOUNDS AND COMPOSITIONS THEREOF AND METHODS FOR TREATING MALARIA AND CHEMOPROPHYLAXIS | THE US SECRETARY OF THE ARMY ON BEHALF OF WALTER REED ARMY INSTITUTE OF RESEARCH (US) | 2018-02-21 | — | — | EP | disclosed |