Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 9/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1986824 | 0.86 | EPHX2 (0.47) | EPHX2P2RX7DDR1 | |
| SCHEMBL16538118 | 0.84 | P2RX7 (0.57) | EPHX2P2RX7HDAC3HDAC1HDAC2 | |
| SCHEMBL1884357 | 0.84 | EPHX2 (0.47) | EPHX2P2RX7HDAC3HDAC1HDAC2 | |
| SCHEMBL1994282 | 0.83 | EPHX2 (0.44) | EPHX2P2RX7MEN1KMT2A | |
| SCHEMBL1991459 | 0.83 | LMNA (0.45) | EPHX2P2RX7 | |
| SCHEMBL1988822 | 0.82 | SETDB1 (0.49) | EPHX2P2RX7DDR1 | |
| SCHEMBL1871892 | 0.82 | EPHX2 (0.43) | EPHX2P2RX7KMT2ATRPV1DDR1 | |
| SCHEMBL1872511 | 0.81 | P2RX7 (0.44) | EPHX2P2RX7DDR1 | |
| SCHEMBL1870046 | 0.81 | P2RX7 (0.44) | EPHX2P2RX7HDAC6KMT2ATRPV1 | |
| SCHEMBL27890400 | 0.81 | EPHX2 (0.40) | EPHX2P2RX7HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152332-A1 | Pesticidal Heterocyclic Compounds | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152332-A1 | Pesticidal Heterocyclic Compounds | DDT, PTMS, CYP4X1 | EPHX2 1725/4885P2RX7 156/4885HDAC3 1418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.