Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MIF | P14174 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | TNF | P01375 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347717 | 0.86 | MAOA (0.41) | MAOACES1BCHEALDH1A1CYP1A2 | |
| SCHEMBL10756250 | 0.82 | MAOA (0.55) | MAOACES1BCHETDP1ALDH1A1 | |
| SCHEMBL7742221 | 0.81 | MAOA (0.53) | MAOACES1BCHEL3MBTL1TDP1 | |
| SCHEMBL5958453 | 0.81 | MAOA (0.53) | MAOACES1BCHETDP1ALDH1A1 | |
| SCHEMBL8012706 | 0.81 | MAOA (0.53) | MAOACES1BCHEALDH1A1CYP1A2 | |
| SCHEMBL11150519 | 0.81 | MAOA (0.53) | MAOACES1BCHEL3MBTL1TDP1 | |
| SCHEMBL11024434 | 0.80 | MAOA (0.49) | MAOACES1BCHEL3MBTL1TDP1 | |
| SCHEMBL3452978 | 0.79 | MAOA (0.52) | MAOACES1BCHEL3MBTL1TDP1 | |
| SCHEMBL11426388 | 0.78 | MAOA (0.50) | MAOACES1BCHEL3MBTL1ALDH1A1 | |
| SCHEMBL10703055 | 0.78 | MAOA (0.59) | MAOACES1BCHEL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2085431-B1 | Benzothioxanthene dyes with improved application and toxicological properties | CLARIANT FINANCE BVI LTD (VG) | 2011-06-29 | — | — | EP | disclosed |
| US-20090255440-A1 | Benzothioxanthene dyes with improved application and toxicological properties | CLARIANT INTERNATIONAL LTD. | 2009-10-15 | — | — | US | disclosed |
| EP-2085431-A1 | Benzothioxanthene dyes with improved application and toxicological properties | CLARIANT INTERNATIONAL LTD. (CH) | 2009-08-05 | — | — | EP | disclosed |
| US-4146547-A | Manufacture of Bz-1-bromobenzanthrone | BASF AKTIENGESELLSCHAFT (DE) | 1979-03-27 | — | — | US | disclosed |