SCHEMBL347717

SCHEMBL347717

Brc1cc2c(c3ccccc13)-c1ccccc1C2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.41
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
KDM4E B2RXH2 2/20 0.39
MAPT P10636 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
HPGD P15428 1/20 0.39
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CYP3A4 P08684 3/20 0.35
CYP2D6 P10635 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
HSD17B10 Q99714 2/20 0.35
MEN1 O00255 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1987356 0.86 MAOA (0.53) MAOANPC1RAB9AKDM4EMAPT
SCHEMBL16115067 0.85 TDP1 (0.42) MAOASRD5A2BCHECES1DAPK3
SCHEMBL21703801 0.82 PNMT (0.41) MAOANPC1RAB9AKDM4EMAPT
SCHEMBL30663206 0.78 MAOA (0.41) MAOANPC1RAB9AKDM4EMAPT
SCHEMBL164399 0.78 MAOA (0.41) MAOANPC1RAB9AKDM4EMAPT
SCHEMBL4848751 0.76 MAOA (0.50) MAOANPC1RAB9AKDM4EMAPT
SCHEMBL16114368 0.74 SRD5A1 (0.41) CA1CA2CA4CA6SRD5A2
SCHEMBL29761258 0.74 SQOR (0.39) MAOANPC1RAB9AKDM4EMAPT
SCHEMBL25492512 0.73 CA1 (0.36) MAOAMAPTSMN1; SMN2ALDH1A1HPGD
SCHEMBL789190 0.72 MAOA (0.46) MAOANPC1RAB9AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11708328-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-07-25 US disclosed
WO-2020130681-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 두산솔루스 주식회사 2020-06-25 WO disclosed
WO-2020130681-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 두산솔루스 주식회사 2020-06-25 WO disclosed
CN-108586712-B Electroluminescent monomer, electroluminescent polymer, and preparation method and application thereof 华南协同创新研究院 2020-06-05 CN disclosed
US-20180083204-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-03-22 US disclosed
US-9530971-B1 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2016-12-27 US disclosed
US-9466803-B1 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2016-10-11 US disclosed
US-20160005981-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2016-01-07 US disclosed
US-8993805-B2 Benzofluorene compound and use thereof TOSOH CORPORATION (JP) 2015-03-31 US disclosed
US-8993805-B2 Benzofluorene compound and use thereof TOSOH CORPORATION (JP) 2015-03-31 US disclosed
US-20140077179-A1 NOVEL COMPOUND FOR ORGANIC ELECTRONIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2014-03-20 US disclosed
US-20120016147-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-19 US disclosed
US-8048982-B2 Method for producing aromatic compound polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-01 US disclosed
EP-2241548-A1 Vanadium di-nuclear complex Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed
EP-2241547-A1 Method for producing aromatic compound polymer Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed
US-20090184312-A1 BENZOFLUORENE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2009-07-23 US disclosed
US-20090184312-A1 BENZOFLUORENE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2009-07-23 US disclosed
US-20090184312-A1 BENZOFLUORENE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2009-07-23 US disclosed
US-20090018309-A1 Method for Producing Aromatic Compound Polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-15 US disclosed
EP-1767560-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER Sumitomo Chemical Company, Limited (JP) 2007-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090018309-A1 Method for Producing Aromatic Compound Polymer PAH, MAOA, AHR MAOA 2/4885NPC1 3935/4885RAB9A 3951/4885
US-11708328-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ELAVL1, TERT, VDAC2 MAOA 389/4885NPC1 3067/4885RAB9A 1173/4885
US-20180083204-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE THEREOF NFE2L2, OR51E2, ESR1 MAOA 773/4885NPC1 2933/4885RAB9A 3362/4885
US-20090184312-A1 BENZOFLUORENE COMPOUND AND USE THEREOF SLC7A1, SLC43A1, SLC7A5 MAOA 4169/4885NPC1 439/4885RAB9A 1656/4885
US-20160005981-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE THEREOF NFE2L2, OR51E2, ESR1 MAOA 773/4885NPC1 2933/4885RAB9A 3362/4885
US-20120016147-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER PAH, MAOA, AHR MAOA 2/4885NPC1 3836/4885RAB9A 3968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.