Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 5/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19873665 | 1.00 | NAAA (0.41) | NAAALPAR1LPAR3CCR1SLC6A3 | |
| SCHEMBL19873592 | 0.92 | LPAR1 (0.40) | NAAALPAR1LPAR3CCR1 | |
| SCHEMBL19873590 | 0.92 | LPAR1 (0.40) | NAAALPAR1LPAR3CCR1 | |
| SCHEMBL19873602 | 0.92 | LPAR1 (0.49) | NAAALPAR1LPAR3 | |
| SCHEMBL19873603 | 0.92 | LPAR1 (0.49) | NAAALPAR1LPAR3 | |
| SCHEMBL19873662 | 0.91 | LPAR1 (0.39) | NAAALPAR1LPAR3CCR1PRCP | |
| SCHEMBL19873660 | 0.91 | LPAR1 (0.39) | NAAALPAR1LPAR3CCR1PRCP | |
| SCHEMBL19873561 | 0.91 | APP (0.38) | NAAALPAR1LPAR3CCR1DRD2 | |
| SCHEMBL19873565 | 0.91 | APP (0.38) | NAAALPAR1LPAR3CCR1DRD2 | |
| SCHEMBL19873621 | 0.89 | TACR1 (0.38) | NAAALPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3360869-B1 | HALOGEN-SUBSTITUTED HETEROCYCLIC COMPOUND USEFUL FOR THE TREATMENT OF DISEASES CAUSED BY LPA. | UBE INDUSTRIES (JP) | 2020-07-29 | — | — | EP | claimed |
| EP-2940013-B1 | HALOGEN-SUBSTITUTED HETEROCYCLIC COMPOUND | UBE INDUSTRIES (JP) | 2018-02-21 | — | — | EP | claimed |