Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 17/20 | 0.45 |
| ▸ | AKT2 | P31751 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10388908 | 0.78 | KDM4E (0.44) | — | |
| SCHEMBL27906101 | 0.76 | PRCP (0.39) | — | |
| SCHEMBL24365048 | 0.72 | MEN1 (0.49) | ROCK2AKT2AKT1HRH3 | |
| Hydrochloric Acid SCHEMBL19875595 | 0.69 | GSK3B (0.37) | — | |
| SCHEMBL20784255 | 0.68 | ROCK2 (0.74) | ROCK2 | |
| SCHEMBL16432987 | 0.65 | AKT2 (0.76) | ROCK2AKT2AKT1 | |
| SCHEMBL15689115 | 0.65 | AKT2 (0.76) | ROCK2AKT2AKT1 | |
| Hydrochloric Acid SCHEMBL19875629 | 0.65 | MAPK1 (0.47) | HRH3 | |
| SCHEMBL29324103 | 0.64 | AKT1 (0.41) | ROCK2AKT2AKT1HRH3 | |
| SCHEMBL29981292 | 0.64 | AKT1 (0.41) | ROCK2AKT2AKT1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180050997-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR INHIBITION OF FASN | FORMA THERAPEUTICS, INC. | 2018-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180050997-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR INHIBITION OF FASN | FASN, FABP1, SCD | ROCK2 1823/4885AKT2 4192/4885AKT1 3817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.