Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | TNF | P01375 | 2/20 | 0.59 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.59 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | ESRRG | P62508 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19875749 | 1.00 | TDP1 (0.63) | TDP1MAPTL3MBTL1TNFKLF5 | |
| SCHEMBL446400 | 0.91 | TDP1 (0.69) | TDP1MAPTL3MBTL1TNFKLF5 | |
| SCHEMBL19875760 | 0.86 | MAPT (0.57) | TDP1MAPTL3MBTL1TNFKLF5 | |
| SCHEMBL19875761 | 0.86 | MAPT (0.57) | TDP1MAPTL3MBTL1TNFKLF5 | |
| SCHEMBL19875701 | 0.85 | POLB (0.60) | TDP1MAPTL3MBTL1TNFKLF5 | |
| SCHEMBL19875702 | 0.85 | POLB (0.60) | TDP1MAPTL3MBTL1TNFKLF5 | |
| SCHEMBL9878491 | 0.84 | TDP1 (0.69) | TDP1MAPTL3MBTL1TNFKLF5 | |
| SCHEMBL19875696 | 0.83 | CA1 (0.51) | L3MBTL1RAB9ANPC1ESRRGNR1H4 | |
| SCHEMBL19875694 | 0.83 | CA1 (0.51) | L3MBTL1RAB9ANPC1ESRRGNR1H4 | |
| SCHEMBL5079256 | 0.83 | TDP1 (0.59) | TDP1MAPTL3MBTL1TNFKLF5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3268398-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-05-15 | — | — | EP | disclosed |
| US-10246532-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-04-02 | — | — | US | disclosed |
| US-20180051106-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180051106-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | C1S, CCNT1, COG1 | TDP1 3420/4885MAPT 3879/4885L3MBTL1 1834/4885 |
| US-10246532-B2 | Catalyst components for the polymerization of olefins | C1S, CCNT1, COG1 | TDP1 3420/4885MAPT 3879/4885L3MBTL1 1834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.