SCHEMBL5079256

SCHEMBL5079256

C=C(OC(=O)c1ccc(C(C)(C)C)cc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.59
MAPT P10636 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
TNF P01375 2/20 0.56
KLF5 Q13887 2/20 0.56
NOD1 Q9Y239 2/20 0.56
KCNK9 Q9NPC2 1/20 0.48
NPSR1 Q6W5P4 1/20 0.47
SRD5A2 P31213 1/20 0.46
RAB9A P51151 4/20 0.45
LMNA P02545 1/20 0.45
ALDH1A1 P00352 3/20 0.45
TSHR P16473 2/20 0.45
HSD17B10 Q99714 1/20 0.45
NPC1 O15118 3/20 0.43
POLB P06746 1/20 0.43
CASP3 P42574 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
ESRRG P62508 2/20 0.43
HDAC1 Q13547 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL446400 0.88 TDP1 (0.69) TDP1MAPTL3MBTL1TNFKLF5
SCHEMBL5079219 0.84 MAPT (0.60) TDP1MAPTL3MBTL1NPSR1RAB9A
SCHEMBL5082794 0.84 MAPT (0.60) TDP1MAPTL3MBTL1NPSR1RAB9A
SCHEMBL382312 0.84 LMNA (0.56) TDP1MAPTLMNAALDH1A1TSHR
SCHEMBL8333327 0.84 TDP1 (0.49) TDP1MAPTL3MBTL1TNFKLF5
SCHEMBL19875751 0.83 TDP1 (0.63) TDP1MAPTL3MBTL1TNFKLF5
SCHEMBL19875749 0.83 TDP1 (0.63) TDP1MAPTL3MBTL1TNFKLF5
SCHEMBL14099145 0.81 CES2 (0.55) TDP1MAPTNPSR1SRD5A2RAB9A
SCHEMBL9878491 0.81 TDP1 (0.69) TDP1MAPTL3MBTL1TNFKLF5
SCHEMBL446399 0.80 HDAC1 (0.57) TDP1MAPTL3MBTL1TNFKLF5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1868984-B1 BENZOIC ACID ESTER COMPOUNDS, COMPOSITIONS, USES AND METHODS RELATED THERETO FERRER INT (ES) 2017-07-19 EP claimed
US-8545816-B2 1-(4-methoxyphenyl)-vinyl 4-tert-butylbenzoate; cosmetic, pharmaceutical, personal care and industrial preparations as sunscreens; ultraviolet radiation protection FERRER INTERNACIONAL, S.A. (ES) 2013-10-01 US claimed
US-20080206158-A1 Benzoic Acid Ester Compounds, Compositions, Uses and Methods Related Thereto FERRER INTERNACIONAL, S.A. (ES) 2008-08-28 US claimed
EP-1868984-A2 BENZOIC ACID ESTER COMPOUNDS, COMPOSITIONS, USES AND METHODS RELATED THERETO FERRER INTERNACIONAL, S.A. (ES) 2007-12-26 EP claimed
EP-1707558-A1 Benzoic acid ester compounds, compositions, uses and methods related thereto FERRER INTERNACIONAL, S.A. (ES) 2006-10-04 EP claimed
WO-2006100225-A2 BENZOIC ACID ESTER COMPOUNDS, COMPOSITIONS, USES AND METHODS RELATED THERETO FERRER INTERNACIONAL, S. A. (ES) 2006-09-28 WO claimed
US-20260028302-A1 PROCESS FOR PREPARING BENZOIC ACID ESTERS AND INTERMEDIATES THEREOF ROKA FURADADA S L (ES) 2026-01-29 US disclosed
US-20250360066-A1 COMPOSITION COMPRISING A PHOTOCHEMICAL ULTRAVIOLET ABSORBER PRECURSOR AND A COMPOUND FOR INCREASING THEIR PHOTOCHEMICAL CONVERSION RATE ROKA FURADADA S L (ES) 2025-11-27 US disclosed
EP-4561523-A1 COMPOSITION COMPRISING A PHOTOCHEMICAL ULTRAVIOLET ABSORBER PRECURSOR AND A COMPOUND FOR INCREASING THEIR PHOTOCHEMICAL CONVERSION RATE Roka Furadada, SL (ES) 2025-06-04 EP disclosed
CN-119677713-A Processes for preparing benzoates and intermediates thereof 罗卡福拉达有限公司 2025-03-21 CN disclosed
WO-2024013382-A9 PROCESS FOR PREPARING BENZOIC ACID ESTERS AND INTERMEDIATES THEREOF ROKA FURADADA, S.L. (ES) 2024-04-18 WO disclosed
WO-2024023286-A1 COMPOSITION COMPRISING A PHOTOCHEMICAL ULTRAVIOLET ABSORBER PRECURSOR AND A COMPOUND FOR INCREASING THEIR PHOTOCHEMICAL CONVERSION RATE ROKA FURADADA, S.L. (ES) 2024-02-01 WO disclosed
WO-2024013382-A1 PROCESS FOR PREPARING BENZOIC ACID ESTERS AND INTERMEDIATES THEREOF ROKA FURADADA, S.L. (ES) 2024-01-18 WO disclosed
EP-1868984-B1 BENZOIC ACID ESTER COMPOUNDS, COMPOSITIONS, USES AND METHODS RELATED THERETO FERRER INT (ES) 2017-07-19 EP disclosed
US-8545816-B2 1-(4-methoxyphenyl)-vinyl 4-tert-butylbenzoate; cosmetic, pharmaceutical, personal care and industrial preparations as sunscreens; ultraviolet radiation protection FERRER INTERNACIONAL, S.A. (ES) 2013-10-01 US disclosed
US-20080206158-A1 Benzoic Acid Ester Compounds, Compositions, Uses and Methods Related Thereto FERRER INTERNACIONAL, S.A. (ES) 2008-08-28 US disclosed
EP-1868984-A2 BENZOIC ACID ESTER COMPOUNDS, COMPOSITIONS, USES AND METHODS RELATED THERETO FERRER INTERNACIONAL, S.A. (ES) 2007-12-26 EP disclosed
EP-1707558-A1 Benzoic acid ester compounds, compositions, uses and methods related thereto FERRER INTERNACIONAL, S.A. (ES) 2006-10-04 EP disclosed
WO-2006100225-A2 BENZOIC ACID ESTER COMPOUNDS, COMPOSITIONS, USES AND METHODS RELATED THERETO FERRER INTERNACIONAL, S. A. (ES) 2006-09-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250360066-A1 COMPOSITION COMPRISING A PHOTOCHEMICAL ULTRAVIOLET ABSORBER PRECURSOR AND A COMPOUND FOR INCREASING THEIR PHOTOCHEMICAL CONVERSION RATE TYR, PAH, ERCC4 TDP1 1235/4885MAPT 387/4885L3MBTL1 4885/4885
US-20080206158-A1 Benzoic Acid Ester Compounds, Compositions, Uses and Methods Related Thereto VKORC1, CYP51A1, CYP19A1 TDP1 1082/4885MAPT 2950/4885L3MBTL1 4173/4885
US-20260028302-A1 PROCESS FOR PREPARING BENZOIC ACID ESTERS AND INTERMEDIATES THEREOF DHCR24, BCKDK, CYP2B6 TDP1 1743/4885MAPT 4867/4885L3MBTL1 2464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.