Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.58 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | BID | P55957 | 3/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.45 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL375253 | 1.00 | LIPG (0.58) | LIPGTHRATHRBNR1H2NR1H3 | |
| SCHEMBL395649 | 1.00 | LIPG (0.58) | LIPGTHRATHRBNR1H2NR1H3 | |
| SCHEMBL10809003 | 1.00 | LIPG (0.58) | LIPGTHRATHRBNR1H2NR1H3 | |
| SCHEMBL5487867 | 1.00 | LIPG (0.58) | LIPGTHRATHRBNR1H2NR1H3 | |
| SCHEMBL139445 | 1.00 | LIPG (0.58) | LIPGTHRATHRBNR1H2NR1H3 | |
| SCHEMBL11369508 | 1.00 | LIPG (0.58) | LIPGTHRATHRBNR1H2NR1H3 | |
| SCHEMBL396330 | 1.00 | LIPG (0.58) | LIPGTHRATHRBNR1H2NR1H3 | |
| SCHEMBL7338375 | 1.00 | LIPG (0.58) | LIPGTHRATHRBNR1H2NR1H3 | |
| SCHEMBL7170683 | 1.00 | LIPG (0.58) | LIPGTHRATHRBNR1H2NR1H3 | |
| SCHEMBL396013 | 1.00 | LIPG (0.58) | LIPGTHRATHRBNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3992288-A1 | CARBOXYLATED 2'-AMINO-LNA NUCLEOTIDES AND OLIGONUCLEOTIDES COMPRISING THE SAME | BioNTech Delivery Technologies GmbH (DE) | 2022-05-04 | — | — | EP | disclosed |
| EP-3500673-B1 | CARBOXYLATED 2'-AMINO-LNA NUCLEOTIDES AND OLIGONUCLEOTIDES COMPRISING THE SAME | BIONTECH DELIVERY TECH GMBH (DE) | 2021-10-06 | — | — | EP | disclosed |
| US-10894962-B2 | Carboxylated 2′-amino-LNA nucleotides and oligonucleotides comprising the same | BIONTECH DELIVERY TECHNOLOGIES GMBH (DE) | 2021-01-19 | — | — | US | disclosed |
| US-20190203208-A1 | CARBOXYLATED 2'-AMINO-LNA NUCLEOTIDES AND OLIGONUCLEOTIDES COMPRISING THE SAME | BIONTECH DELIVERY TECHNOLOGIES GMBH (DE) | 2019-07-04 | — | — | US | disclosed |
| EP-3500673-A1 | CARBOXYLATED 2'-AMINO-LNA NUCLEOTIDES AND OLIGONUCLEOTIDES COMPRISING THE SAME | Panzner, Steffen (DE) | 2019-06-26 | — | — | EP | disclosed |
| WO-2018033492-A1 | CARBOXYLATED 2'-AMINO-LNA NUCLEOTIDES AND OLIGONUCLEOTIDES COMPRISING THE SAME | PANZNER STEFFEN (DE) | 2018-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190203208-A1 | CARBOXYLATED 2'-AMINO-LNA NUCLEOTIDES AND OLIGONUCLEOTIDES COMPRISING THE SAME | DCTD, NSUN2, SLC29A2 | LIPG 3374/4885THRA 2588/4885THRB 3192/4885 |
| US-10894962-B2 | Carboxylated 2′-amino-LNA nucleotides and oligonucleotides comprising the same | DCTD, NSUN2, TRDMT1 | LIPG 3188/4885THRA 2512/4885THRB 3192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.