Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | ADA | P00813 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21883558 | 0.90 | SLC6A4 (0.38) | LMNASLC6A4SLC6A3OPRM1MAPK1 | |
| SCHEMBL19768940 | 0.81 | LMNA (0.41) | LMNACNR2DPP4DPP8L3MBTL1 | |
| Butyramide SCHEMBL27747515 | 0.72 | DPP4 (0.41) | LMNAKCNH2DPP4DPP8L3MBTL1 | |
| SCHEMBL18488029 | 0.70 | SYK (0.36) | KCNH2PIM1 | |
| SCHEMBL20693674 | 0.69 | DPP4 (0.46) | LMNAKCNH2DPP4DPP8L3MBTL1 | |
| SCHEMBL7584037 | 0.68 | LMNA (0.48) | LMNASLC6A4SLC6A3SLC6A2DPP4 | |
| SCHEMBL18449467 | 0.67 | PIM1 (0.34) | KCNH2DPP4PIM1 | |
| SCHEMBL29287224 | 0.67 | HTR2B (0.38) | HSD17B10DPP4MAPK1 | |
| SCHEMBL12569462 | 0.66 | PIM1 (0.39) | LMNAMAPK1PIM1 | |
| SCHEMBL19490297 | 0.66 | SLC6A4 (0.39) | SLC6A4SLC6A3OPRM1ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9896432-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2018-02-20 | — | — | US | disclosed |