Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21173558 | 0.75 | NOS3 (0.39) | NOS3NOS2 | |
| SCHEMBL22096909 | 0.74 | NOS2 (0.36) | NOS3NOS2 | |
| SCHEMBL13073442 | 0.73 | KMT2A (0.37) | — | |
| SCHEMBL4989950 | 0.72 | NOS2 (0.56) | NOS3NOS2 | |
| SCHEMBL8835609 | 0.72 | NOS3 (0.35) | NOS3NOS2 | |
| SCHEMBL21709863 | 0.70 | NOS3 (0.31) | NOS3NOS2 | |
| SCHEMBL19779245 | 0.70 | NOS3 (0.31) | NOS3NOS2 | |
| SCHEMBL20621309 | 0.66 | — | — | |
| SCHEMBL5064766 | 0.64 | TP53 (0.43) | — | |
| SCHEMBL22661734 | 0.62 | TP53 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9896432-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2018-02-20 | — | — | US | disclosed |