Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | CCR8 | P51685 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18174571 | 0.84 | NPC1 (0.44) | NPC1KDM4EGRM5PKMRAB9A | |
| SCHEMBL21022955 | 0.84 | NPC1 (0.49) | NPC1KDM4EPKMRAB9AMEN1 | |
| SCHEMBL18657149 | 0.81 | NPC1 (0.46) | NPC1KDM4EGRM5PKMRAB9A | |
| SCHEMBL18571558 | 0.80 | BTK (0.49) | NPC1KDM4EGRM5PKMRAB9A | |
| SCHEMBL30090498 | 0.79 | NPC1 (0.47) | NPC1KDM4EGRM5PKMRAB9A | |
| SCHEMBL8252636 | 0.79 | NPC1 (0.47) | NPC1KDM4EGRM5PKMRAB9A | |
| SCHEMBL17086997 | 0.78 | TGFBR1 (0.46) | NPC1KDM4EGRM5PKMRAB9A | |
| SCHEMBL10032909 | 0.77 | KDM4E (0.46) | NPC1KDM4EPKMRAB9AMEN1 | |
| SCHEMBL15588885 | 0.77 | GRM5 (0.52) | NPC1KDM4EGRM5MEN1KMT2A | |
| SCHEMBL16882962 | 0.77 | GRM5 (0.43) | NPC1KDM4EGRM5PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2991997-B1 | TRANSITION METAL COMPLEXES WITH CARBENE LIGANDS AND THE USE THEREOF IN OLEDS | UDC IRELAND LTD (IE) | 2018-02-21 | — | — | EP | disclosed |