SCHEMBL18657149

SCHEMBL18657149

Cc1ccc(-c2ccccc2)cc1-c1ccccn1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.46
KDM4E B2RXH2 3/20 0.46
RAB9A P51151 4/20 0.44
PKM P14618 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
LMNA P02545 2/20 0.44
TP53 P04637 2/20 0.44
MAPT P10636 2/20 0.44
TSHR P16473 2/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
KLF5 Q13887 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CYP1A2 P05177 1/20 0.43
POLB P06746 1/20 0.43
CCR1 P32246 1/20 0.43
CCR5 P51681 1/20 0.43
CCR8 P51685 1/20 0.43
METAP1 P53582 1/20 0.43
BLM P54132 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16882962 0.95 GRM5 (0.43) NPC1KDM4ERAB9APKMSMN1; SMN2
SCHEMBL18571558 0.92 BTK (0.49) NPC1KDM4ERAB9APKMSMN1; SMN2
SCHEMBL21742845 0.90 MAPK14 (0.44) NPC1KDM4ERAB9APKMSMN1; SMN2
SCHEMBL21022955 0.89 NPC1 (0.49) NPC1KDM4ERAB9APKMSMN1; SMN2
SCHEMBL15588885 0.89 GRM5 (0.52) NPC1KDM4EGRM5MEN1KMT2A
SCHEMBL17856726 0.89 RAB9A (0.43) NPC1KDM4ERAB9APKMSMN1; SMN2
SCHEMBL18174583 0.87 BTK (0.38) NPC1KDM4ERAB9APKMSMN1; SMN2
SCHEMBL18633527 0.86 KDM4E (0.46) NPC1KDM4ERAB9APKMSMN1; SMN2
SCHEMBL21742630 0.86 MAPK14 (0.48) NPC1KDM4ERAB9APKMSMN1; SMN2
SCHEMBL21338505 0.84 TRPV1 (0.45) NPC1KDM4ERAB9APKMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023146343-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2023-08-03 WO disclosed
WO-2023146296-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-08-03 WO disclosed
WO-2023085046-A1 ORGANIC COMPOUND, ORGANIC LIGHT EMITTING ELEMENT, DISPLAY DEVICE, PHOTOELECTRIC CONVERSION DEVICE, ELECTRONIC APPARATUS, ILLUMINATION DEVICE, MOVABLE BODY, AND EXPOSURE LIGHT SOURCE キヤノン株式会社 2023-05-19 WO disclosed
WO-2022086168-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2022-04-28 WO disclosed
WO-2022086171-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2022-04-28 WO disclosed
US-11239433-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-02-01 US disclosed
US-11239432-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-02-01 US disclosed
US-20170084849-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2017-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11239433-B2 Organic electroluminescent materials and devices L1CAM, OR10J3, EML4 NPC1 3636/4885KDM4E 3752/4885RAB9A 1902/4885
US-11239432-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 NPC1 2141/4885KDM4E 4450/4885RAB9A 3901/4885
US-20170084849-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, LAGE3, TIMCC NPC1 4591/4885KDM4E 860/4885RAB9A 1425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.