SCHEMBL1988499

SCHEMBL1988499

CCCCc1ccccc1N(CCN(C(=N)NC(=N)N)c1ccccc1CCCC)C(=N)NC(=N)N

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPY2R P49146 1/20 0.39
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
LIPG Q9Y5X9 1/20 0.35
TLR8 Q9NR97 2/20 0.34
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33
TP53 P04637 2/20 0.31
HTR1A P08908 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1983845 0.95 LIPG (0.42) NPY2RLIPGTLR8TP53ALDH1A1
SCHEMBL11510903 0.84 NPY2R (0.33) NPY2RCYP2D6TP53ALDH1A1POLB
SCHEMBL30764858 0.77 KMT2A (0.39) CYP3A4TP53ALDH1A1POLB
SCHEMBL837932 0.77 KMT2A (0.39) CYP3A4TP53ALDH1A1POLB
SCHEMBL11660926 0.77 MEN1 (0.40) CYP3A4CYP2D6GRIN2DGRIN3BGRIN1
SCHEMBL1704944 0.76 SIGMAR1 (0.46) TP53ALDH1A1
SCHEMBL31626902 0.76 SIGMAR1 (0.46) TP53ALDH1A1
SCHEMBL11663862 0.75 CYP3A4 (0.33) CYP3A4CYP2D6CYP2C9LIPGGRIN2D
SCHEMBL837766 0.74 TP53 (0.42) CYP3A4TP53ALDH1A1POLB
SCHEMBL7009170 0.74 NPC1 (0.44) CYP3A4CYP2C9GRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230276794-A1 MESH MATERIALS FOR CONTROLLED RELEASE OF ANTIVIRALS, METHOD AND USE 2HEAL INDUSTRIA E COMERCIO DE PRODUTOS QUIMICOS PARA USO INDUSTRIAL LTDA (BR) 2023-09-07 US claimed
EP-4186382-A1 MESH MATERIALS FOR CONTROLLED RELEASE OF ANTIVIRALS, METHOD AND USE Universidade Federal de Minas Gerais (BR) 2023-05-31 EP claimed
WO-2022018689-A1 MESH MATERIALS FOR CONTROLLED RELEASE OF ANTIVIRALS, METHOD AND USE UNIVERSIDADE FEDERAL DE MINAS GERAIS (BR) 2022-01-27 WO claimed
US-6987099-B2 Uncomplexed cyclodextrin compositions for odor control THE PROCTER & GAMBLE COMPANY (US) 2006-01-17 US claimed
US-6656923-B1 With compatible surfactant; water soluble antimicrobial; perfume; optional additives and wrinkle control agent selected from: compatible fiber lubricants, shape retention polymers, lithium salts, and mixtures thereof THE PROCTER & GAMBLE COMPANY 2003-12-02 US claimed
US-20230276794-A1 MESH MATERIALS FOR CONTROLLED RELEASE OF ANTIVIRALS, METHOD AND USE 2HEAL INDUSTRIA E COMERCIO DE PRODUTOS QUIMICOS PARA USO INDUSTRIAL LTDA (BR) 2023-09-07 US disclosed
EP-4186382-A1 MESH MATERIALS FOR CONTROLLED RELEASE OF ANTIVIRALS, METHOD AND USE Universidade Federal de Minas Gerais (BR) 2023-05-31 EP disclosed
WO-2022018689-A1 MESH MATERIALS FOR CONTROLLED RELEASE OF ANTIVIRALS, METHOD AND USE UNIVERSIDADE FEDERAL DE MINAS GERAIS (BR) 2022-01-27 WO disclosed
EP-2515782-B1 POWDER-FREE GLOVE WITH STABLE AND FAST-ACTING ANTIMICROBIAL COATING ANSELL LTD (AU) 2015-12-16 EP disclosed
EP-2126030-B1 LOW RESIDUE CLEANING SOLUTION CLOROX CO (US) 2014-07-09 EP disclosed
US-8546355-B2 Functionally available cyclodextrin combined with compatible and incompatible surfactants; cleaning hard surfaces, carpets, fabrics, hair, skin, dishes; direct use and/or impregnated into wiping material THE PROCTER AND GAMBLE COMPANY (US) 2013-10-01 US disclosed
EP-2515782-A2 POWDER-FREE GLOVE WITH STABLE AND FAST-ACTING ANTIMICROBIAL COATING Ansell Limited (AU) 2012-10-31 EP disclosed
US-5192533-A Hypophite-acrylic polymer CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1993-03-09 US disclosed
EP-0373429-A2 Oral treatment method for reducing plaque with reduced staining THE PROCTER & GAMBLE COMPANY (US) 1990-06-20 EP disclosed
US-4886658-A MIXTURE OF MONOPEROXYPHTHALATE AND BISGUANID COMPOUND THE PROCTER & GAMBLE COMPANY (US) 1989-12-12 US disclosed
US-4110083-A HARD MINERAL PARTICLES COATED WITH A CATIONIC WATER-SOLUBLE POLYMER THE PROCTER & GAMBLE COMPANY (US) 1978-08-29 US disclosed
US-4051234-A BIS-GUANIDINE COMPOUND, ETHYLENEDIAMINEDIACETIC ACID OR SALT AS CHELATOR THE PROCTER & GAMBLE COMPANY (US) 1977-09-27 US disclosed
US-4025616-A Oral compositions for plaque, caries and calculus retardation with reduced staining tendencies THE PROCTER & GAMBLE COMPANY (US) 1977-05-24 US disclosed
US-3937807-A BISBIGUANIDE COMPOUND THE PROCTER & GAMBLE COMPANY (US) 1976-02-10 US disclosed
US-3934002-A BIS-GUANIDE THE PROCTER & GAMBLE COMPANY (US) 1976-01-20 US disclosed