Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.52 |
| ▸ | FAAH | O00519 | 4/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | F7 | P08709 | 2/20 | 0.39 |
| ▸ | F3 | P13726 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19890256 | 0.94 | TLR8 (0.58) | TLR8FAAHMMP2F7F3 | |
| SCHEMBL23505037 | 0.84 | PPARG (0.55) | TLR8FAAHDAGLACES1PPARG | |
| SCHEMBL27947021 | 0.78 | TLR8 (0.61) | TLR8TRPV1MAPT | |
| SCHEMBL1767928 | 0.78 | TLR8 (0.82) | TLR8 | |
| SCHEMBL1767937 | 0.78 | TLR8 (0.82) | TLR8 | |
| SCHEMBL28198533 | 0.77 | TLR8 (0.47) | TLR8FAAHKDM4EDAGLACES1 | |
| SCHEMBL28198532 | 0.77 | TLR8 (0.47) | TLR8FAAHKDM4EDAGLACES1 | |
| SCHEMBL28386512 | 0.77 | TLR8 (0.56) | TLR8FAAHKDM4EDAGLACES1 | |
| SCHEMBL9287141 | 0.74 | FAAH (0.45) | TLR8FAAHKDM4EMAPTDAGLA | |
| SCHEMBL19890145 | 0.74 | FAAH (0.54) | FAAHDAGLACES1OXER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018033642-A1 | HETEROCYCLIC LIPXON ANALOGS AND USES THEROF | UNIVERSITY COLLEGE DUBLIN (IE) | 2018-02-22 | — | — | WO | disclosed |