Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18005303 | 0.84 | MAPT (0.46) | MAPTLTA4HCHRM1CHRM2 | |
| SCHEMBL18005455 | 0.77 | ATM (0.39) | MAPTCHRM1 | |
| SCHEMBL18005647 | 0.73 | ALDH1A1 (0.44) | MAPT | |
| SCHEMBL18029910 | 0.72 | MEN1 (0.36) | — | |
| SCHEMBL18005390 | 0.72 | MEN1 (0.36) | — | |
| SCHEMBL18005354 | 0.71 | MEN1 (0.36) | CHRM1 | |
| SCHEMBL1707790 | 0.69 | ALDH1A1 (0.49) | — | |
| SCHEMBL19900683 | 0.67 | CHRM1 (0.30) | CHRM1 | |
| SCHEMBL19900182 | 0.66 | NPY5R (0.36) | MAPTCHRM1 | |
| SCHEMBL19900162 | 0.66 | NPY5R (0.36) | MAPTCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016133959-A9 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-02-22 | — | — | WO | disclosed |