⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1395649 | 0.79 | NPC1 (0.54) | — | |
| SCHEMBL1022195 | 0.79 | NPC1 (0.54) | — | |
| SCHEMBL1630772 | 0.79 | NPC1 (0.54) | — | |
| SCHEMBL1517918 | 0.78 | CA12 (0.48) | — | |
| SCHEMBL104713 | 0.78 | NPC1 (0.48) | — | |
| SCHEMBL104712 | 0.78 | NPC1 (0.48) | — | |
| SCHEMBL1920276 | 0.77 | — | — | |
| SCHEMBL1132777 | 0.74 | — | — | |
| SCHEMBL2655451 | 0.74 | — | — | |
| SCHEMBL22062236 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230123588-A1 | METHODS OF SLOWING BRAIN VOLUME LOSS | VANDA PHARMACEUTICALS INC. | 2023-04-20 | — | — | US | claimed |
| CN-106715424-B | Bicyclic compounds as pesticides | 拜耳作物科学股份公司 | 2020-07-14 | — | — | CN | claimed |
| EP-3152216-B1 | BICYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2019-07-24 | — | — | EP | claimed |
| US-10294243-B2 | Bicyclic compounds as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-05-21 | — | — | US | claimed |
| US-10206398-B2 | Five-membered C-N-attached aryl sulphide and aryl sulphoxide derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-02-19 | — | — | US | claimed |
| EP-3230267-B1 | FIVE-MEMBERED C-N LINKED ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2018-09-26 | — | — | EP | claimed |
| US-20170367333-A1 | FIVE-MEMBERED C-N-ATTACHED ARYL SULPHIDE AND ARYL SULPHOXIDE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-12-28 | — | — | US | claimed |
| EP-3230267-A1 | FIVE-MEMBERED C-N BONDED ARYL SULPHIDE AND ARYL SULPHOXIDE DERIVATIVES AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2017-10-18 | — | — | EP | claimed |
| US-20170101422-A1 | Bicyclic compounds as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-04-13 | — | — | US | claimed |
| EP-3152216-A1 | BICYCLIC COMPOUNDS AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2017-04-12 | — | — | EP | claimed |
| WO-2015185531-A1 | BICYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2015-12-10 | — | — | WO | claimed |
| US-5859190-A | SOLID PHASE SYNTHESIS TO FORM A PROTECTED DIPEPTIDE FOLLOWED BY REACTING WITH 1,1'-THIOCARBONYLDIIMIDAZOLE TO EFFECT RING FORMATION; EFFICIENCY; ANTICONVULSANT,-ARRHYTHMIC AND DIABETIC AGENTS; HERBICIDES AND FUNGICIDES | TREGA BIOSCIENCES, INC. (US) | 1999-01-12 | — | — | US | claimed |
| WO-1998033776-A1 | COMBINATORIAL LIBRARIES OF HYDANTOIN AND THIOHYDANTOIN DERIVATIVES, METHODS OF MAKING THE LIBRARIES AND COMPOUNDS THEREIN | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |
| EP-0832082-A1 | N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ZENECA LIMITED (GB) | 1998-04-01 | — | — | EP | claimed |
| WO-1996040681-A1 | N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ZENECA LIMITED (GB) | 1996-12-19 | — | — | WO | claimed |
| WO-1994010142-A1 | NEW SUBSTITUTED AZETIDINONES AS ANTI-INFLAMMATORY AND ANTIDEGENERATIVE AGENTS | MERCK & CO., INC. (US) | 1994-05-11 | — | — | WO | claimed |
| EP-0517052-A1 | Substituted imidazolinyl-pyrimidines | BAYER AG (DE) | 1992-12-09 | — | — | EP | claimed |
| US-4493835-A | CARDIOTONIC, HYPOTENSIVE AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-01-15 | — | — | US | claimed |
| EP-0077963-A1 | 2-Nitro-5-(4-trifluoromethyl-phenoxy)-benzyl derivatives, process for their preparation, and their use as herbicides and plant growth regulators | BAYER AG (DE) | 1983-05-04 | — | — | EP | claimed |
| US-4315855-A | Monoazo disperse dyes containing a nitrophenyl group and a homophthalimide group | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | claimed |