Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | CCR8 | P51685 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29151793 | 0.87 | TGFBR1 (0.44) | TDP1THRBMEN1BLMKMT2A | |
| SCHEMBL12268978 | 0.84 | TDP1 (0.37) | TDP1THRBMEN1BLMKMT2A | |
| SCHEMBL12268970 | 0.84 | TDP1 (0.37) | TDP1THRBMEN1BLMKMT2A | |
| SCHEMBL12269159 | 0.83 | TDP1 (0.39) | TDP1THRBMEN1BLMKMT2A | |
| SCHEMBL12268994 | 0.83 | TDP1 (0.39) | TDP1THRBMEN1BLMKMT2A | |
| SCHEMBL4745967 | 0.83 | CYP1A2 (0.42) | TDP1THRBMEN1BLMKMT2A | |
| SCHEMBL15497843 | 0.81 | CCR1 (0.57) | TDP1MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL29413360 | 0.79 | ALDH1A1 (0.61) | TDP1THRBMEN1KMT2ACYP3A4 | |
| SCHEMBL29814212 | 0.79 | ALDH1A1 (0.61) | TDP1THRBMEN1KMT2ACYP3A4 | |
| SCHEMBL2124728 | 0.79 | ALDH1A1 (0.61) | TDP1THRBMEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286787-A1 | ELECTRON TRANSPORT LAYER AND FILM HAVING IMPROVED THERMAL STABILITY | Rohm and Haas Electronic Materials LLC (US) | 2018-02-28 | — | — | EP | disclosed |
| CN-105612628-A | Charge-transporting varnish | NISSAN CHEMICAL IND LTD | 2016-05-25 | — | — | CN | disclosed |