Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18113159 | 0.90 | TSHR (0.65) | TSHRALDH1A1NPSR1LMNAHSD17B10 | |
| SCHEMBL18113182 | 0.85 | ALDH1A1 (0.58) | TSHRALDH1A1NPSR1LMNAHSD17B10 | |
| SCHEMBL18113301 | 0.83 | TSHR (0.62) | TSHRALDH1A1NPSR1LMNAHSD17B10 | |
| SCHEMBL18113099 | 0.83 | TSHR (0.62) | TSHRALDH1A1NPSR1LMNAHSD17B10 | |
| SCHEMBL11633418 | 0.82 | TSHR (0.71) | TSHRALDH1A1NPSR1LMNAHSD17B10 | |
| SCHEMBL944028 | 0.82 | TSHR (0.71) | TSHRALDH1A1NPSR1LMNAHSD17B10 | |
| SCHEMBL18113235 | 0.81 | TSHR (0.61) | TSHRALDH1A1NPSR1LMNAHSD17B10 | |
| SCHEMBL7754646 | 0.80 | TSHR (0.69) | TSHRALDH1A1NPSR1LMNAHSD17B10 | |
| SCHEMBL2027590 | 0.80 | TSHR (0.71) | TSHRALDH1A1NPSR1LMNAHSD17B10 | |
| SCHEMBL1959525 | 0.80 | TSHR (0.69) | TSHRALDH1A1NPSR1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3277736-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-03-27 | — | — | EP | disclosed |
| US-10011668-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-07-03 | — | — | US | disclosed |
| US-20180057622-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-03-01 | — | — | US | disclosed |