SCHEMBL19896285

SCHEMBL19896285

CC(c1ccccc1)n1c2cc(Br)ccc2c2ccc(Br)cc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 2/20 0.40
▸ MEN1 O00255 5/20 0.40
▸ KMT2A Q03164 5/20 0.40
▸ HSD17B10 Q99714 2/20 0.40
▸ LMNA P02545 2/20 0.40
▸ CYP2D6 P10635 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ CASP1 P29466 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ POLB P06746 1/20 0.37
▸ MC4R P32245 1/20 0.36
▸ HDAC3 O15379 2/20 0.36
▸ HDAC4 P56524 2/20 0.36
▸ HDAC1 Q13547 2/20 0.36
▸ HDAC7 Q8WUI4 2/20 0.36
▸ HDAC2 Q92769 2/20 0.36
▸ HDAC10 Q969S8 2/20 0.36
▸ HDAC11 Q96DB2 2/20 0.36
▸ HDAC8 Q9BY41 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19911128 0.79 BRD4 (0.40) BRD4MEN1KMT2AHSD17B10LMNA
Hydrochloric Acid SCHEMBL19896462 0.78 BRD4 (0.40) BRD4MEN1KMT2AHSD17B10LMNA
SCHEMBL19350540 0.77 PDGFRA (0.38) MEN1KMT2ALMNACASP1
SCHEMBL27900581 0.77 MEN1 (0.49) BRD4MEN1KMT2AHSD17B10LMNA
SCHEMBL28019916 0.77 MEN1 (0.49) MEN1KMT2ACASP1L3MBTL1POLB
SCHEMBL19896281 0.76 OPRM1 (0.38) BRD4LMNANPSR1
SCHEMBL14247296 0.74 MEN1 (0.45) BRD4MEN1KMT2AHSD17B10LMNA
SCHEMBL14247421 0.74 MEN1 (0.45) BRD4MEN1KMT2AHSD17B10LMNA
SCHEMBL14247294 0.74 MEN1 (0.45) BRD4MEN1KMT2AHSD17B10LMNA
SCHEMBL19411751 0.74 PIK3CD (0.45) MEN1KMT2AHSD17B10LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421779-B2 Carbazole compound having anti-virus activity KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2019-09-24 — — US disclosed
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-03-01 — — US disclosed
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-03-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY ZC3HAV1, ZC3HAV1L, GTF3C3 BRD4 204/4885MEN1 4741/4885KMT2A 2739/4885
US-10421779-B2 Carbazole compound having anti-virus activity ZC3HAV1, ZC3HAV1L, GTF3C3 BRD4 204/4885MEN1 4741/4885KMT2A 2739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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