SCHEMBL19896281

SCHEMBL19896281

CCCC(c1ccccc1)n1c2cc(Br)ccc2c2ccc(Br)cc21

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 3/20 0.38
▸ OPRD1 P41143 3/20 0.38
▸ OPRK1 P41145 3/20 0.38
▸ OPRL1 P41146 3/20 0.38
▸ SLC6A2 P23975 6/20 0.37
▸ SLC6A4 P31645 3/20 0.37
▸ BRD4 O60885 1/20 0.37
▸ CYP17A1 P05093 1/20 0.35
▸ CYP19A1 P11511 2/20 0.35
▸ CACNA2D1 P54289 4/20 0.34
▸ LMNA P02545 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ HTR2A P28223 1/20 0.33
▸ TSPO P30536 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19896280 0.89 OPRM1 (0.43) OPRM1OPRD1OPRK1OPRL1SLC6A2
SCHEMBL19896433 0.89 OPRM1 (0.43) OPRM1OPRD1OPRK1OPRL1SLC6A2
Hydrochloric Acid SCHEMBL19896465 0.81 KDM4E (0.40) OPRM1OPRD1OPRK1OPRL1SLC6A2
SCHEMBL19896285 0.76 BRD4 (0.40) BRD4LMNANPSR1
SCHEMBL19896448 0.75 OPRD1 (0.36) OPRM1OPRD1OPRK1OPRL1SLC6A2
SCHEMBL19896301 0.72 OXER1 (0.33) MAPTSMN1; SMN2TDP1TSPO
Hydrochloric Acid SCHEMBL19896410 0.71 OPRM1 (0.42) OPRM1OPRD1OPRK1OPRL1SLC6A2
SCHEMBL29386524 0.70 OXER1 (0.36) LMNA
SCHEMBL12131327 0.70 OXER1 (0.36) LMNA
SCHEMBL5132795 0.70 KMT2A (0.37) SLC6A2SLC6A4CACNA2D1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421779-B2 Carbazole compound having anti-virus activity KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2019-09-24 — — US disclosed
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-03-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY ZC3HAV1, ZC3HAV1L, GTF3C3 OPRM1 4146/4885OPRD1 3087/4885OPRK1 2750/4885
US-10421779-B2 Carbazole compound having anti-virus activity ZC3HAV1, ZC3HAV1L, GTF3C3 OPRM1 4146/4885OPRD1 3087/4885OPRK1 2750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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