SCHEMBL19896301

SCHEMBL19896301

CCCCC(CCCC)n1c2cc(Br)ccc2c2ccc(Br)cc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ OXER1 Q8TDS5 3/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ NFKB1 P19838 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ NFKB2 Q00653 1/20 0.32
▸ RELA Q04206 1/20 0.32
▸ PDGFRA P16234 1/20 0.32
▸ CDK5 Q00535 1/20 0.32
▸ TYRO3 Q06418 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ SIGMAR1 Q99720 1/20 0.31
▸ DNM1 Q05193 3/20 0.31
▸ MAPT P10636 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ TSPO P30536 1/20 0.31
▸ CNR1 P21554 1/20 0.31
▸ CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29386524 0.94 OXER1 (0.36) OXER1CNR1CNR2
SCHEMBL12131327 0.94 OXER1 (0.36) OXER1CNR1CNR2
SCHEMBL28155228 0.89 OXER1 (0.33) OXER1SMN1; SMN2NPC1GAANFKB1
SCHEMBL17578546 0.88 OXER1 (0.35) OXER1CNR1CNR2
SCHEMBL17760860 0.84 OXER1 (0.35) OXER1CNR1CNR2
SCHEMBL14680674 0.81 OXER1 (0.40) OXER1SMN1; SMN2SIGMAR1DNM1MAPT
SCHEMBL19911137 0.80 MAPT (0.38) SMN1; SMN2NPC1GAARAB9AKMT2A
SCHEMBL6365319 0.80 OXER1 (0.38) OXER1SMN1; SMN2KMT2ACNR1CNR2
Hydrochloric Acid SCHEMBL19896359 0.79 MAPT (0.38) GAAKMT2ASIGMAR1MAPTALDH1A1
SCHEMBL673712 0.76 DNM1 (0.38) OXER1SMN1; SMN2SIGMAR1DNM1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421779-B2 Carbazole compound having anti-virus activity KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2019-09-24 — — US disclosed
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-03-01 — — US disclosed
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-03-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY ZC3HAV1, ZC3HAV1L, GTF3C3 OXER1 3437/4885SMN1; SMN2 4589/4885NPC1 191/4885
US-10421779-B2 Carbazole compound having anti-virus activity ZC3HAV1, ZC3HAV1L, GTF3C3 OXER1 3437/4885SMN1; SMN2 4589/4885NPC1 191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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