SCHEMBL673712

SCHEMBL673712

CCCCCC(CC)n1c2ccc(Br)cc2c2cc(Br)ccc21

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ DNM1 Q05193 3/20 0.38
▸ MAPT P10636 2/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ SIGMAR1 Q99720 1/20 0.37
▸ OXER1 Q8TDS5 2/20 0.37
▸ CNR2 P34972 4/20 0.36
▸ P2RX3 P56373 1/20 0.35
▸ GSK3B P49841 4/20 0.34
▸ TSPO P30536 1/20 0.34
▸ CNR1 P21554 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17912279 0.93 TSPO (0.43) DNM1MAPTCNR2TSPOCNR1
SCHEMBL14680674 0.92 OXER1 (0.40) DNM1MAPTSMN1; SMN2SIGMAR1OXER1
SCHEMBL28155228 0.88 OXER1 (0.33) SMN1; SMN2OXER1CNR2GSK3BCNR1
SCHEMBL17578546 0.87 OXER1 (0.35) OXER1CNR2GSK3BCNR1
SCHEMBL22369532 0.84 ICMT (0.40) DNM1MAPTSMN1; SMN2SIGMAR1
SCHEMBL4811708 0.82 CNR1 (0.32) CNR2CNR1
SCHEMBL29386524 0.80 OXER1 (0.36) OXER1CNR2GSK3BCNR1
SCHEMBL12131327 0.80 OXER1 (0.36) OXER1CNR2GSK3BCNR1
SCHEMBL14003740 0.78 PTGER4 (0.45) CNR2CNR1
SCHEMBL3117565 0.78 LPL (0.40) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8053547-B2 Conjugated polymers and blends containing carbazole, representation and use thereof MERCK PATENT GMBH (DE) 2011-11-08 — — US disclosed
EP-1932866-B1 Blends comprising conjugated carbazole polymers, synthesis and usage thereof MERCK PATENT GMBH (DE) 2011-07-13 — — EP disclosed
US-20110068304-A1 Conjugated Polymers and Blends Containing Carbazole, Representation and Use Thereof MERCK PATENT GMBH (DE) 2011-03-24 — — US disclosed
US-7834136-B2 Conjugated polymers and blends containing carbazole, representation and use thereof COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2010-11-16 — — US disclosed
US-7679082-B2 Multi-functional copolymers comprising rare earth metal complexes and devices thereof NATIONAL UNIVERSITY OF SINGAPORE (SG) 2010-03-16 — — US disclosed
EP-1932866-A1 Blends comprising conjugated carbazole polymers, synthesis and usage thereof MERCK PATENT GmbH (DE) 2008-06-18 — — EP disclosed
EP-1592729-B1 CONJUGATED POLYMERS AND BLENDS CONTAINING CARBAZOLE, REPRESENTATION AND USE THEREOF MERCK PATENT GMBH (DE) 2008-04-23 — — EP disclosed
CN-101128506-A Multifunctional copolymers containing rare earth metal complexes and devices thereof UNIV SINGAPORE (SG) 2008-02-20 — — CN disclosed
US-20070290199-A1 Multi-Functional Copolymers Comprising Rare Earth Metal Complexes and Devices Thereof NATIONAL UNIVERSITY OF SINGAPORE (SG) 2007-12-20 — — US disclosed
US-20060149022-A1 Polymeric (organic) light emitting diodes, (PLED, OLED); polyarylenevinylene polymer containing N-substituted carbazole units, and another aromatic ring unit; blends with organometallic fluorescent or phosphorescent molecule such as phenylpyridine iridium complex MERCK PATENT GMBH (DE) 2006-07-06 — — US disclosed
WO-2006052222-A2 MULTI-FUNCTIONAL COPOLYMERS COMPRISING RARE EARTH METAL COMPLEXES AND DEVICES THEREOF NATIONAL UNIVERSITY OF SINGAPORE (SG) 2006-05-18 — — WO disclosed
EP-1592729-A2 CONJUGATED POLYMERS AND BLENDS CONTAINING CARBAZOLE, REPRESENTATION AND USE THEREOF Covion Organic Semiconductors GmbH (DE) 2005-11-09 — — EP disclosed
WO-2004070772-A2 CONJUGATED POLYMERS AND BLENDS CONTAINING CARBAZOLE, REPRESENTATION AND USE THEREOF COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2004-08-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070290199-A1 Multi-Functional Copolymers Comprising Rare Earth Metal Complexes and Devices Thereof ZRANB2, BAZ1A, BAZ2B DNM1 283/4885MAPT 4099/4885SMN1; SMN2 2039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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