SCHEMBL19896366

SCHEMBL19896366

O=[N+]([O-])c1cccc(Cn2c3cc(Br)ccc3c3ccc(Br)cc32)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX4 Q9NPH5 1/20 0.56
PIK3R1 P27986 1/20 0.54
PIK3CA P42336 1/20 0.54
ALDH1A1 P00352 4/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
KDM4E B2RXH2 2/20 0.53
MAPK1 P28482 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
KMT2A Q03164 4/20 0.51
MEN1 O00255 2/20 0.51
POLB P06746 1/20 0.51
CFTR P13569 1/20 0.50
MAPT P10636 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TSHR P16473 1/20 0.48
CCR2 P41597 1/20 0.47
LMNA P02545 1/20 0.47
HPGD P15428 2/20 0.46
TDP1 Q9NUW8 1/20 0.45
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30616061 0.83 KMT2A (0.69) NOX4ALDH1A1SMN1; SMN2KMT2AMEN1
SCHEMBL29093452 0.83 KMT2A (0.69) NOX4ALDH1A1SMN1; SMN2KMT2AMEN1
Hydrochloric Acid SCHEMBL19896382 0.83 NOX4 (0.55) NOX4ALDH1A1SMN1; SMN2KDM4EKMT2A
SCHEMBL8802144 0.76 KMT2A (0.54) NOX4ALDH1A1SMN1; SMN2KDM4EMAPK1
SCHEMBL8387035 0.76 KMT2A (0.54) NOX4ALDH1A1SMN1; SMN2KDM4EMAPK1
SCHEMBL19896424 0.76 CYP19A1 (0.60) ALDH1A1SMN1; SMN2KMT2AMEN1LMNA
SCHEMBL19896309 0.76 CYP11B1 (0.41) SMN1; SMN2TDP1
SCHEMBL19896377 0.76 SRC (0.45)
SCHEMBL29136044 0.75 KMT2A (0.48) NOX4PIK3R1PIK3CAALDH1A1SMN1; SMN2
SCHEMBL19896454 0.75 NOX4 (0.50) NOX4ALDH1A1SMN1; SMN2KDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421779-B2 Carbazole compound having anti-virus activity KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2019-09-24 US disclosed
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-03-01 US disclosed
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY ZC3HAV1, ZC3HAV1L, GTF3C3 NOX4 2110/4885PIK3R1 1619/4885PIK3CA 2995/4885
US-10421779-B2 Carbazole compound having anti-virus activity ZC3HAV1, ZC3HAV1L, GTF3C3 NOX4 2110/4885PIK3R1 1619/4885PIK3CA 2995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.