Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8387035 | 1.00 | KMT2A (0.54) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8388468 | 0.88 | MAPT (0.57) | KMT2AALDH1A1HPGDNOX4P2RX4 | |
| SCHEMBL30616061 | 0.86 | KMT2A (0.69) | KMT2AALDH1A1HPGDNOX4P2RX4 | |
| SCHEMBL29093452 | 0.86 | KMT2A (0.69) | KMT2AALDH1A1HPGDNOX4P2RX4 | |
| SCHEMBL8386934 | 0.84 | KDM4E (0.65) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8802871 | 0.83 | SIGMAR1 (0.50) | KMT2AALDH1A1KDM4EHPGDNOX4 | |
| SCHEMBL8389022 | 0.82 | KDM4E (0.56) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8387038 | 0.80 | KMT2A (0.54) | KMT2AALDH1A1HPGDNOX4P2RX4 | |
| SCHEMBL2651119 | 0.79 | TSHR (0.61) | ALDH1A1HPGDSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL296300 | 0.79 | TSHR (0.61) | ALDH1A1HPGDSMN1; SMN2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804416-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY LIMITED (JP) | 1997-11-05 | — | — | EP | disclosed |