Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.62 |
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | PBK | Q96KB5 | 2/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11399322 | 1.00 | TAAR1 (0.62) | TAAR1ACHESTAT3GRIA4CYP1A2 | |
| Hydrochloric Acid SCHEMBL5878048 | 0.98 | TAAR1 (0.60) | TAAR1ACHESTAT3GRIA4CYP1A2 | |
| SCHEMBL3006604 | 0.89 | TAAR1 (0.75) | TAAR1TDP1 | |
| Hydrochloric Acid SCHEMBL6564727 | 0.87 | TAAR1 (0.71) | TAAR1TDP1 | |
| SCHEMBL5146825 | 0.81 | ACHE (0.46) | TAAR1ACHESTAT3GRIA4CYP1A2 | |
| SCHEMBL17504534 | 0.81 | TAAR1 (0.42) | TAAR1ACHESTAT3GRIA4CYP1A2 | |
| Hydrochloric Acid SCHEMBL5877955 | 0.80 | TAAR1 (0.62) | TAAR1TDP1 | |
| SCHEMBL4527843 | 0.80 | TAAR1 (0.62) | TAAR1ACHEGRIA4TDP1 | |
| SCHEMBL20425554 | 0.78 | TAAR1 (0.60) | TAAR1CYP1A2CYP2A6ALOX5MAOA | |
| SCHEMBL21286098 | 0.78 | TAAR1 (0.60) | TAAR1CYP1A2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790900-B2 | Method for producing an optically active nitro compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-07 | — | — | US | claimed |
| WO-2024097228-A1 | COMPOUNDS TARGETING CDK11 AND METHODS OF USING THE SAME | MELIORA THERAPEUTICS, INC. (US) | 2024-05-10 | — | — | WO | disclosed |
| EP-3609868-B1 | TETRAHYDROQUINOLINE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | RAQUALIA PHARMA INC (JP) | 2023-10-18 | — | — | EP | disclosed |
| WO-2023191721-A2 | PRODUCTION OF ENANTIOPURE ALCOHOLS, AMINES AND ACIDS FROM ALKENES BY CASCADE BIOTRANSFORMATION INVOLVING 1,2-METHYL SHIFT | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2023-10-05 | — | — | WO | disclosed |
| CN-111848494-B | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-111848494-A | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2020-10-30 | — | — | CN | disclosed |
| US-20200039943-A1 | COMPOUNDS, DEVICES, AND USES THEREOF | SIGILON THERAPEUTICS, INC. | 2020-02-06 | — | — | US | disclosed |
| CN-105473575-B | Benzimidazolyl-methylurea derivatives as ALX receptor agonists | 爱杜西亚药品有限公司 | 2017-11-24 | — | — | CN | disclosed |
| EP-2943483-B1 | BENZYLAMINE DERIVATIVES | KALVISTA PHARMACEUTICALS LTD (GB) | 2017-03-01 | — | — | EP | disclosed |
| US-8361959-B2 | Spiro-imidazolone derivatives as glucagon receptor antagonists | MERCK SHARP & DOHME CORP. (US) | 2013-01-29 | — | — | US | disclosed |
| EP-2055689-B1 | Method for producing an optically active nitro compound | SUMITOMO CHEMICAL CO (JP) | 2011-06-29 | — | — | EP | disclosed |
| US-7790900-B2 | Method for producing an optically active nitro compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-07 | — | — | US | disclosed |
| EP-2055689-A1 | Method for producing an optically active nitro compound | Sumitomo Chemical Company, Limited (JP) | 2009-05-06 | — | — | EP | disclosed |
| EP-1641740-B1 | METHOD FOR PRODUCING AN OPTICALLY ACTIVE NITRO COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2009-03-25 | — | — | EP | disclosed |
| US-20070037976-A1 | such as 1-amino-2-phenylpropane by reacting unsaturated nitroolefin with organosilicon compounds such as poly(methylhydrosiloxane) and phenylsilane, in presence of asymmetric copper complex having phosphine ligand | SUMITOMO CHEMICAL COMPANY, LIMITED ERICK M. CARREIRA | 2007-02-15 | — | — | US | disclosed |
| EP-1641740-A1 | METHOD FOR PRODUCING AN OPTICALLY ACTIVE NITRO COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2006-04-05 | — | — | EP | disclosed |
| WO-2004103951-A1 | METHOD FOR PRODUCING AN OPTICALLY ACTIVE NITRO COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-12-02 | — | — | WO | disclosed |
| EP-0882715-B1 | NOVEL N-(UNSUBSTITUTED OR SUBSTITUTED)-4-SUBSTITUTED-6-(UNSUBSTITUTED OR SUBSTITUTED)PHENOXY-2-PYRIDINECARBOXAMIDES OR THIOCARBOXAMIDES, PROCESSES FOR PRODUCING THE SAME, AND HERBICIDES | KUREHA CHEMICAL IND CO LTD (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6339045-B1 | CAN BE USED IN A SMALL AMOUNT, SHOWING A GOOD SELECTIVITY BETWEEN CROP AND WEED, AND CAUSING NO PHYTOTOXICITY | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2002-01-15 | — | — | US | disclosed |
| EP-0882715-A1 | NOVEL N-(UNSUBSTITUTED OR SUBSTITUTED)-4-SUBSTITUTED-6-(UNSUBSTITUTED OR SUBSTITUTED)PHENOXY-2-PYRIDINECARBOXAMIDES OR THIOCARBOXAMIDES, PROCESSES FOR PRODUCING THE SAME, AND HERBICIDES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039943-A1 | COMPOUNDS, DEVICES, AND USES THEREOF | SLC10A1, SLCO1B3, SLC5A1 | TAAR1 473/4885ACHE 336/4885STAT3 2457/4885 |
| US-20070037976-A1 | such as 1-amino-2-phenylpropane by reacting unsaturated nitroolefin with organosilicon compounds such as poly(methylhydrosiloxane) and phenylsilane, in presence of asymmetric copper complex having phosphine ligand | L1CAM, SPATS2L, AAAS | TAAR1 637/4885ACHE 3226/4885STAT3 1167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.