SCHEMBL19898985

SCHEMBL19898985

CCCCC(F)(F)C(=O)Cl

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CES2 O00748 5/20 0.52
ALDH1A1 P00352 2/20 0.42
TP53 P04637 1/20 0.42
FAAH O00519 8/20 0.41
CES1 P23141 6/20 0.40
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40
KMT2A Q03164 1/20 0.40
HSD17B10 Q99714 1/20 0.40
FDPS P14324 1/20 0.40
TSHR P16473 1/20 0.39
LPAR1 Q92633 1/20 0.38
LPAR3 Q9UBY5 1/20 0.38
EPHX1 P07099 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31578835 0.91 CES2 (0.64) CES2ALDH1A1FAAHCES1MEN1
SCHEMBL6004493 0.85
SCHEMBL11297795 0.79 ALDH1A1 (0.41) CES2ALDH1A1TP53FAAHCES1
SCHEMBL1706449 0.78 CES2 (0.54) CES2FAAHCES1MEN1CYP1A2
SCHEMBL12396593 0.78 CES2 (0.54) CES2FAAHCES1MEN1CYP1A2
SCHEMBL9508311 0.77 CES2 (0.39) CES2ALDH1A1TP53FAAHCES1
SCHEMBL9508307 0.77 CES2 (0.39) CES2ALDH1A1TP53FAAHCES1
SCHEMBL439276 0.76 CES2 (0.52) CES2FAAHCES1MEN1CYP1A2
SCHEMBL431610 0.76 CES2 (0.42) CES2
SCHEMBL628993 0.75 ALDH1A1 (0.46) CES2ALDH1A1TP53CES1FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11480878-B2 Monomers, polymers and photoresist compositions ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-10-25 US disclosed
CN-107793527-A Monomer, polymer and photo-corrosion-resisting agent composition 罗门哈斯电子材料韩国有限公司 2018-03-13 CN disclosed
US-20180059545-A1 MONOMERS, POLYMERS AND PHOTORESIST COMPOSITIONS DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2018-03-01 US disclosed
US-20180059545-A1 MONOMERS, POLYMERS AND PHOTORESIST COMPOSITIONS DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2018-03-01 US disclosed
US-20180059545-A1 MONOMERS, POLYMERS AND PHOTORESIST COMPOSITIONS DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2018-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11480878-B2 Monomers, polymers and photoresist compositions PARG, LCP1, ALG3 CES2 1510/4885ALDH1A1 894/4885TP53 2329/4885
US-20180059545-A1 MONOMERS, POLYMERS AND PHOTORESIST COMPOSITIONS PARG, LCP1, ALG3 CES2 1510/4885ALDH1A1 894/4885TP53 2329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.