⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26084940 | 1.00 | — | — | |
| SCHEMBL12130450 | 1.00 | — | — | |
| SCHEMBL24840273 | 1.00 | — | — | |
| SCHEMBL20561087 | 0.98 | — | — | |
| SCHEMBL17022762 | 0.98 | — | — | |
| SCHEMBL8216248 | 0.91 | — | — | |
| SCHEMBL8204004 | 0.91 | — | — | |
| SCHEMBL25238564 | 0.88 | LMNA (0.36) | — | |
| SCHEMBL30229515 | 0.85 | LMNA (0.32) | — | |
| SCHEMBL11932236 | 0.83 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902985-B2 | Chemoenzymatic methods for synthesizing moenomycin analogs | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-02-27 | — | — | US | disclosed |