SCHEMBL25238564

SCHEMBL25238564

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)CCCCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30229515 0.97 LMNA (0.32) LMNA
SCHEMBL11932236 0.94 LMNA (0.33) LMNA
SCHEMBL30057609 0.90 LMNA (0.31) LMNA
SCHEMBL10709739 0.88 THRB (0.30) THRB
SCHEMBL22277214 0.88 CES2 (0.41) THRB
SCHEMBL5570616 0.88 THRB (0.30) THRB
SCHEMBL3814139 0.88 THRB (0.30) THRB
SCHEMBL24840273 0.88
SCHEMBL21511269 0.88 CA12 (0.36) LMNA
SCHEMBL23560381 0.88 CES2 (0.41) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023114944-A1 FLUORINATED CATIONIC LIPIDS FOR USE IN LIPID NANOPARTICLES Acuitas Therapeutics, Inc. (CA) 2023-06-22 WO claimed
WO-2023114944-A1 FLUORINATED CATIONIC LIPIDS FOR USE IN LIPID NANOPARTICLES Acuitas Therapeutics, Inc. (CA) 2023-06-22 WO disclosed
WO-2023114937-A2 FLUORINATED CATIONIC LIPIDS FOR USE IN LIPID NANOPARTICLES Acuitas Therapeutics, Inc. (CA) 2023-06-22 WO disclosed