Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15679230 | 1.00 | PRCP (0.50) | PRCPSLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL19888932 | 0.85 | SLC6A2 (0.42) | PRCPSLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL19901375 | 0.85 | SLC6A2 (0.42) | PRCPSLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL15679232 | 0.85 | SLC6A2 (0.42) | PRCPSLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL19901377 | 0.85 | SIGMAR1 (0.45) | SLC6A2SLC6A4SLC6A3SIGMAR1MAPT | |
| SCHEMBL15679233 | 0.85 | SIGMAR1 (0.45) | SLC6A2SLC6A4SLC6A3SIGMAR1MAPT | |
| SCHEMBL11730138 | 0.82 | SLC6A2 (0.39) | PRCPSLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL15679226 | 0.82 | KCNH2 (0.50) | SLC6A2SLC6A4SLC6A3SIGMAR1MAPT | |
| SCHEMBL19901378 | 0.82 | KCNH2 (0.50) | SLC6A2SLC6A4SLC6A3SIGMAR1MAPT | |
| SCHEMBL17126938 | 0.81 | SLC6A2 (0.45) | PRCPSLC6A2SLC6A4SLC6A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902699-B2 | Synthesis of tetrahydroisoquinolines from 2-methyl-1-phenyl substituted indenes | Gregory Rosocha (CA) | 2018-02-27 | — | — | US | disclosed |
| US-9902699-B2 | Synthesis of tetrahydroisoquinolines from 2-methyl-1-phenyl substituted indenes | Gregory Rosocha (CA) | 2018-02-27 | — | — | US | disclosed |