Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15679226 | 1.00 | KCNH2 (0.50) | KCNH2SLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL19901377 | 0.86 | SIGMAR1 (0.45) | KCNH2SLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL15679233 | 0.86 | SIGMAR1 (0.45) | KCNH2SLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL19901375 | 0.83 | SLC6A2 (0.42) | KCNH2SLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL19888932 | 0.83 | SLC6A2 (0.42) | KCNH2SLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL15679232 | 0.83 | SLC6A2 (0.42) | KCNH2SLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL15679230 | 0.82 | PRCP (0.50) | KCNH2SLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL19901374 | 0.82 | PRCP (0.50) | KCNH2SLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL11730138 | 0.78 | SLC6A2 (0.39) | KCNH2SLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL15679224 | 0.77 | SLC6A2 (0.50) | KCNH2SLC6A2SLC6A4SLC6A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902699-B2 | Synthesis of tetrahydroisoquinolines from 2-methyl-1-phenyl substituted indenes | Gregory Rosocha (CA) | 2018-02-27 | — | — | US | disclosed |
| US-9902699-B2 | Synthesis of tetrahydroisoquinolines from 2-methyl-1-phenyl substituted indenes | Gregory Rosocha (CA) | 2018-02-27 | — | — | US | disclosed |