SCHEMBL19901459

SCHEMBL19901459

CC(C)N(c1ccccc1F)c1c(F)ccc(-c2ccccc2)c1-c1ccc(-c2cccc3ccccc23)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
PPARG P37231 7/20 0.38
PPARA Q07869 7/20 0.38
CA12 O43570 4/20 0.34
CA1 P00915 4/20 0.34
CA2 P00918 4/20 0.34
CA9 Q16790 4/20 0.34
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
PPARD Q03181 1/20 0.33
MCL1 Q07820 1/20 0.33
ACMSD Q8TDX5 1/20 0.33
ENPP3 O14638 1/20 0.33
ENPP1 P22413 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19901366 0.88 PTGS2 (0.36) AKR1C3AKR1C2CYP2C9CYP2C19NPSR1
SCHEMBL19901501 0.88 LMNA (0.38) AKR1C3AKR1C2CYP2C9CYP2C19NPSR1
SCHEMBL15856340 0.85 PPARG (0.36) AKR1C3AKR1C2PPARGPPARACA12
SCHEMBL15856342 0.85 PPARG (0.36) AKR1C3AKR1C2PPARGPPARACA12
SCHEMBL15853072 0.82 PPARG (0.38) AKR1C3AKR1C2PPARGPPARACA12
SCHEMBL15853069 0.82 PPARG (0.38) AKR1C3AKR1C2PPARGPPARACA12
SCHEMBL19901446 0.81 AKR1C3 (0.41) AKR1C3AKR1C2PPARGPPARACA12
SCHEMBL15856454 0.80 AKR1C3 (0.36) AKR1C3AKR1C2PPARGPPARACA12
SCHEMBL15856415 0.79 AKR1C3 (0.37) AKR1C3AKR1C2PPARGPPARACA12
SCHEMBL19901480 0.78 CA12 (0.39) AKR1C3AKR1C2PPARGPPARACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9905776-B2 Pyrene-based compound and organic light-emitting diode comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-02-27 US disclosed