Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16006820 | 0.92 | PTGS1 (0.44) | PTGS1PTGS2FAAHMGLLHTT | |
| SCHEMBL19901568 | 0.89 | PTGS1 (0.40) | PTGS1PTGS2FAAHMGLLHTT | |
| SCHEMBL16006863 | 0.86 | PTGS1 (0.54) | PTGS1PTGS2FAAHMGLLHTT | |
| SCHEMBL17347440 | 0.86 | PTGS1 (0.46) | PTGS1PTGS2FAAHMGLLHTT | |
| SCHEMBL16006806 | 0.85 | PTGS1 (0.44) | PTGS1PTGS2FAAHMGLLHTT | |
| SCHEMBL20471076 | 0.83 | PTGS1 (0.44) | PTGS1PTGS2FAAHMGLLHTT | |
| SCHEMBL16006752 | 0.81 | PTGS1 (0.38) | PTGS1PTGS2FAAHMGLLHTT | |
| SCHEMBL13471893 | 0.81 | MGLL (0.48) | PTGS1PTGS2FAAHMGLLHTT | |
| SCHEMBL17347454 | 0.79 | AKT1 (0.43) | PTGS1PTGS2HTTHPGDSMN1; SMN2 | |
| SCHEMBL13471892 | 0.78 | PTGS1 (0.49) | PTGS1PTGS2FAAHMGLLHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9901647-B2 | Conjugates comprising cell-binding agents and cytotoxic agents | IMMUNOGEN, INC. (US) | 2018-02-27 | — | — | US | disclosed |