Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | LSS | P48449 | 3/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17177287 | 1.00 | ALDH1A1 (0.36) | ALDH1A1LMNATDP1PI4KAPI4K2B | |
| SCHEMBL17157276 | 1.00 | ALDH1A1 (0.36) | ALDH1A1LMNATDP1PI4KAPI4K2B | |
| SCHEMBL17173379 | 1.00 | ALDH1A1 (0.36) | ALDH1A1LMNATDP1PI4KAPI4K2B | |
| SCHEMBL17157275 | 1.00 | ALDH1A1 (0.36) | ALDH1A1LMNATDP1PI4KAPI4K2B | |
| SCHEMBL19901607 | 1.00 | ALDH1A1 (0.36) | ALDH1A1LMNATDP1PI4KAPI4K2B | |
| SCHEMBL17157274 | 1.00 | ALDH1A1 (0.36) | ALDH1A1LMNATDP1PI4KAPI4K2B | |
| SCHEMBL17173383 | 0.91 | PLA2G2A (0.33) | PRKCGPTPN1 | |
| SCHEMBL22179404 | 0.91 | PLA2G2A (0.33) | PRKCGPTPN1 | |
| SCHEMBL17157238 | 0.91 | PLA2G2A (0.33) | PRKCGPTPN1 | |
| SCHEMBL17037328 | 0.90 | ALDH1A1 (0.37) | ALDH1A1LMNATDP1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902752-B2 | 5-fluorouracil derivatives | B. BRAUN MELSUNGEN AG (DE) | 2018-02-27 | — | — | US | disclosed |