SCHEMBL19901679

SCHEMBL19901679

Cc1ccc(-c2nc(-c3ccc(C)cc3C)nc(-c3ccc(C)cc3C)n2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.49
RAB9A P51151 6/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
SMN1; SMN2 Q16637 4/20 0.41
MAPT P10636 3/20 0.41
TP53 P04637 3/20 0.41
L3MBTL1 Q9Y468 4/20 0.40
MAPK1 P28482 2/20 0.40
ATM Q13315 1/20 0.40
ADORA3 P0DMS8 1/20 0.39
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
GAA P10253 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
DPP4 P27487 1/20 0.38
CYP1A1 P04798 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP1B1 Q16678 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15894216 0.96 RAB9A (0.49) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL15026010 0.92 NPC1 (0.49) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL4210533 0.91 KDM4E (0.44) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL15025867 0.90 RAB9A (0.47) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL29354045 0.89 NPC1 (0.47) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL1245257 0.89 NPC1 (0.47) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL28459413 0.89 ESR2 (0.50) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL8672171 0.89 ESR2 (0.50) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL18571778 0.89 L3MBTL1 (0.53) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL29991932 0.89 L3MBTL1 (0.53) NPC1RAB9AMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9905767-B2 High-molecular compound and light-emitting element using same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-27 US disclosed