Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL618758 | 0.92 | HPGD (0.38) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL619252 | 0.92 | HPGD (0.38) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL618757 | 0.92 | HPGD (0.38) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL620495 | 0.90 | ALDH1A1 (0.37) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL621416 | 0.90 | TAS1R3 (0.37) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL620609 | 0.90 | TAS1R3 (0.37) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL620496 | 0.90 | ALDH1A1 (0.37) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL19901693 | 0.88 | TP53 (0.37) | ALDH1A1POLBMEN1KMT2AMAPT | |
| SCHEMBL21149029 | 0.85 | NPC1 (0.43) | KDM4EMEN1KMT2ALMNAGAA | |
| SCHEMBL21281165 | 0.84 | MCHR1 (0.44) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902737-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2018-02-27 | — | — | US | disclosed |