Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA3 | P07451 | 2/20 | 0.30 |
| ▸ | CA4 | P22748 | 2/20 | 0.30 |
| ▸ | CA6 | P23280 | 2/20 | 0.30 |
| ▸ | CA5A | P35218 | 2/20 | 0.30 |
| ▸ | CA7 | P43166 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9945684 | 1.00 | LMNA (0.39) | LMNATSHRALDH1A1MAPK1NFKB1 | |
| SCHEMBL22215550 | 0.92 | LMNA (0.43) | LMNATSHRALDH1A1MAPK1NFKB1 | |
| SCHEMBL23978135 | 0.90 | LMNA (0.42) | LMNATSHRALDH1A1CA12CA1 | |
| SCHEMBL3362217 | 0.82 | — | — | |
| SCHEMBL23021103 | 0.82 | — | — | |
| SCHEMBL1146663 | 0.82 | LMNA (0.47) | LMNATSHRALDH1A1NFKB1HTR2A | |
| SCHEMBL16240597 | 0.81 | ALDH1A1 (0.41) | LMNATSHRALDH1A1MAPK1NFKB1 | |
| SCHEMBL830510 | 0.81 | LMNA (0.32) | LMNAALDH1A1NFKB1HTR2AHRH1 | |
| SCHEMBL21011204 | 0.79 | LMNA (0.31) | LMNA | |
| SCHEMBL24835043 | 0.79 | RNPEP (0.32) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902096-B2 | Production of fibre composite component part based on aluminium and polyurethane | EVONIK DEGUSSA GMBH (DE) | 2018-02-27 | — | — | US | disclosed |