SCHEMBL1990236

SCHEMBL1990236

FC(C(F)(F)F)C(F)(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7788043 0.77
SCHEMBL1803311 0.77 ALDH1A1 (0.33) ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL9100254 0.77 ALDH1A1 (0.33) ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL404187 0.77 ALDH1A1 (0.33) ALDH1A1HSD17B10MEN1KMT2A
Apaflurane SCHEMBL19860 0.74 ALDH1A1 (0.33) ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL9125122 0.72 ALDH1A1 (0.30) ALDH1A1HSD17B10
SCHEMBL8633437 0.72 TSHR (0.31) ALDH1A1HSD17B10
SCHEMBL9746085 0.72 ALDH1A1 (0.30) ALDH1A1HSD17B10
SCHEMBL20710006 0.72 ALDH1A1 (0.30) ALDH1A1HSD17B10
Apaflurane SCHEMBL17867718 0.70 ALDH1A1 (0.31) ALDH1A1HSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170333941-A1 HIGH ENERGY EFFICIENCY PHASE CHANGE DEVICE USING CONVEX SURFACE FEATURES U.S. DEPARTMENT OF ENERGY 2017-11-23 US claimed
EP-2976317-B1 COMPOSITION COMPRISING HF AND 2,3,3,3-TETRAFLUOROPROPENE ARKEMA FRANCE (FR) 2021-03-24 EP disclosed
EP-2976318-B1 COMPOSITION COMPRISING HF AND 1,3,3,3-TETRAFLUOROPROPENE ARKEMA FRANCE (FR) 2020-12-09 EP disclosed
US-10596536-B2 Composition comprising HF and 3,3,3-trifluoro-2-chloropropene ARKEMA FRANCE (FR) 2020-03-24 US disclosed
US-10590052-B2 Azeotropic compositions of hydrogen fluoride and Z-3,3,3-trifluoro-1-chloropropene ARKEMA FRANCE (FR) 2020-03-17 US disclosed
US-10550054-B2 Composition comprising HF and 3,3,3-trifluoropropene ARKEMA FRANCE (FR) 2020-02-04 US disclosed
US-10343963-B2 Composition comprising HF and E-3,3,3-trifluoro-1-chloropropene ARKEMA FRANCE (FR) 2019-07-09 US disclosed
US-10330364-B2 System and method for retrofitting a refrigeration system from HCFC to HFC refrigerant HUDSON TECHNOLOGIES, INC. (US) 2019-06-25 US disclosed
US-20190178544-A1 SYSTEM AND METHOD FOR RETROFITTING A REFRIGERATION SYSTEM FROM HCFC TO HFC REFRIGERANT HUDSON TECHNOLOGIES, INC. 2019-06-13 US disclosed
US-10266465-B2 Composition comprising HF and 1,3,3,3-tetrafluoropropene ARKEMA FRANCE (FR) 2019-04-23 US disclosed
WO-1991018967-A1 AZEOTROPE-LIKE COMPOSITIONS OF DICHLOROPENTAFLUOROPROPANE, ETHANOL AND 1,2-DICHLOROETHYLENE ALLIED-SIGNAL INC. (US) 1991-12-12 WO disclosed
EP-0452632-A2 Dichloro-pentafluoropropanes-containing compositions Kali-Chemie Aktiengesellschaft (DE) 1991-10-23 EP disclosed
EP-0450296-A2 Dichlorofluoropropanes based compositions for removing water from surfaces Kali-Chemie Aktiengesellschaft (DE) 1991-10-09 EP disclosed
EP-0450458-A1 Compositions of dichloropenta fluoropropane and acetone Kali-Chemie Aktiengesellschaft (DE) 1991-10-09 EP disclosed
EP-0444598-A1 Azeotropic solvent composition DAIKIN INDUSTRIES, LIMITED (JP) 1991-09-04 EP disclosed
WO-1991009988-A1 AZEOTROPE-LIKE COMPOSITIONS OF DICHLOROPENTAFLUOROPROPANE, ETHANOL AND A HYDROCARBON CONTAINING SIX CARBON ATOMS ALLIED-SIGNAL INC. (US) 1991-07-11 WO disclosed
EP-0427069-A2 Detergent composition comprising fluorinated hydrocarbons containing hydrogen and partially fluorinated alcanols Kali-Chemie Aktiengesellschaft (DE) 1991-05-15 EP disclosed
WO-1991005082-A1 AZEOTROPE-LIKE COMPOSITIONS OF DICHLOROPENTAFLUOROPROPANE AND 1,2-DICHLOROETHYLENE ALLIED-SIGNAL INC. (US) 1991-04-18 WO disclosed
WO-1991005035-A1 AZEOTROPE-LIKE COMPOSITIONS OF DICHLOROPENTAFLUOROPROPANE AND AN ALKANOL HAVING 1-4 CARBON ATOMS ALLIED-SIGNAL INC. (US) 1991-04-18 WO disclosed
WO-1991005083-A1 AZEOTROPE-LIKE COMPOSITIONS OF DICHLOROPENTAFLUOROPROPANE AND A HYDROCARBON CONTAINING SIX CARBON ATOMS ALLIED-SIGNAL INC. (US) 1991-04-18 WO disclosed