SCHEMBL7547478

SCHEMBL7547478

CCCCCCCCCCCCCCc1ccccc1-c1ccc2ccccc2c1N

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.45
TLR8 Q9NR97 10/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
USP2 O75604 1/20 0.43
ALDH1A1 P00352 1/20 0.43
GLA P06280 1/20 0.43
CYP3A4 P08684 1/20 0.43
GAA P10253 1/20 0.43
HPGD P15428 1/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
HSD17B10 Q99714 1/20 0.43
LIPG Q9Y5X9 1/20 0.43
NR1H2 P55055 1/20 0.43
NR1H3 Q13133 1/20 0.43
GPR3 P46089 1/20 0.40
CNR2 P34972 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8915572 1.00 CNR1 (0.45) CNR1TLR8MAPTKDM4EUSP2
SCHEMBL1989997 1.00 CNR1 (0.45) CNR1TLR8MAPTKDM4EUSP2
SCHEMBL1990197 1.00 CNR1 (0.45) CNR1TLR8MAPTKDM4EUSP2
SCHEMBL1678984 1.00 CNR1 (0.45) CNR1TLR8MAPTKDM4EUSP2
SCHEMBL7549186 1.00 CNR1 (0.45) CNR1TLR8MAPTKDM4EUSP2
SCHEMBL1994553 1.00 CNR1 (0.45) CNR1TLR8MAPTKDM4EUSP2
SCHEMBL1990277 0.99 TLR8 (0.44) CNR1TLR8MAPTKDM4EUSP2
SCHEMBL1992947 0.94 TLR8 (0.43) CNR1TLR8MAPTKDM4EUSP2
SCHEMBL17554803 0.89 CNR1 (0.44) CNR1TLR8MAPTKDM4EUSP2
SCHEMBL11248732 0.83 KDM4E (0.51) TLR8MAPTKDM4EUSP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1216224-A2 METHOD OF MANUFACTURING ALKYLATED PHENYLNAPHTHYLAMINE COMPOSITIONS; AND PRODUCTS Noveon IP Holdings Corp. (US) 2002-06-26 EP disclosed
WO-2001023343-A2 METHOD OF MANUFACTURING ALKYLATED PHENYLNAPHTHYLAMINE COMPOSITIONS; AND PRODUCTS NOVEON IP HOLDINGS CORP. (US) 2001-04-05 WO disclosed