SCHEMBL1992947

SCHEMBL1992947

CCCCc1ccccc1-c1ccc2ccccc2c1N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 4/20 0.43
CNR2 P34972 1/20 0.41
CNR1 P21554 2/20 0.39
TLR7 Q9NYK1 1/20 0.39
GAA P10253 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KDM4E B2RXH2 1/20 0.37
USP2 O75604 1/20 0.37
ALDH1A1 P00352 1/20 0.37
GLA P06280 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
HSD17B10 Q99714 1/20 0.37
NCEH1 Q6PIU2 1/20 0.36
BCHE P06276 2/20 0.36
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1990277 0.95 TLR8 (0.44) TLR8CNR2CNR1GAAKDM4E
SCHEMBL1989997 0.94 CNR1 (0.45) TLR8CNR2CNR1GAAKDM4E
SCHEMBL1678984 0.94 CNR1 (0.45) TLR8CNR2CNR1GAAKDM4E
SCHEMBL7547478 0.94 CNR1 (0.45) TLR8CNR2CNR1GAAKDM4E
SCHEMBL8915572 0.94 CNR1 (0.45) TLR8CNR2CNR1GAAKDM4E
SCHEMBL1994553 0.94 CNR1 (0.45) TLR8CNR2CNR1GAAKDM4E
SCHEMBL7549186 0.94 CNR1 (0.45) TLR8CNR2CNR1GAAKDM4E
SCHEMBL1990197 0.94 CNR1 (0.45) TLR8CNR2CNR1GAAKDM4E
SCHEMBL17554803 0.84 CNR1 (0.44) TLR8CNR1GAAKDM4EUSP2
SCHEMBL1406259 0.82 TLR8 (0.49) TLR8TLR7GAATDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2055764-B1 OIL-BASED LUBRICANT FOR FORGING, FORGING METHOD AND USE OF THE LUBRICANT AOKI SCIENCE INST CO LTD (JP) 2014-10-15 EP disclosed
US-8841242-B2 Anti-wear agent, additive composition for lubricant, and lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2014-09-23 US disclosed
US-8728994-B2 Oil type lubricant for forging, forging method and spray apparatus AOKI SCIENCE INSTITUTE CO., LTD. (JP) 2014-05-20 US disclosed
EP-2520638-A1 Anti-wear agent, additive composition for lubricant, and lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2012-11-07 EP disclosed
US-20110152145-A1 ANTI-WEAR AGENT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2011-06-23 US disclosed
EP-2177594-A1 ANTI-WEAR AGENT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2010-04-21 EP disclosed
US-20090118149-A1 Oil Type Lubricant for Forging, Forging Method and Spray Apparatus AOKI SCIENCES INSTITUTE CO.,LTD. (JP) 2009-05-07 US disclosed
EP-2055764-A1 OIL-BASED LUBRICANT FOR FORGING, FORGING METHOD, AND COATING APPARATUS Aoki Science Institute Co, Ltd (JP) 2009-05-06 EP disclosed
US-20060252659-A1 Lubricating oil for dynamic fluid-pressure bearing, dynamic-fluid-pressure bearing, motor, and information recording/reproducing apparatus SEIKO INSTRUMENTS, INC. (JP) 2006-11-09 US disclosed