Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6591541 | 0.74 | TIPARP (0.43) | TIPARPMEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL24570981 | 0.71 | TIPARP (0.36) | TIPARPMEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL30800800 | 0.69 | ESR1 (0.41) | ALDH1A1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL29165379 | 0.69 | ESR1 (0.41) | ALDH1A1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL11997024 | 0.66 | SLC6A2 (0.46) | ALDH1A1MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL10278431 | 0.66 | SLC6A2 (0.46) | ALDH1A1MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL18559580 | 0.66 | SLC6A2 (0.46) | ALDH1A1MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL28848016 | 0.66 | ALDH1A1 (0.45) | ALDH1A1RAB9AMAPTNPC1OPRM1 | |
| Fumaric Acid SCHEMBL6587762 | 0.65 | LMNA (0.40) | TIPARPMEN1KMT2ASLC6A2MAPT | |
| SCHEMBL25686833 | 0.65 | MAPT (0.42) | TIPARPMEN1KMT2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3033337-B1 | SUBSTITUTED IMIDAZOLES AS N-TYPE CALCIUM CHANNEL BLOCKERS | JANSSEN PHARMACEUTICA NV (BE) | 2018-02-28 | — | — | EP | disclosed |