Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19903078 | 0.71 | LMNA (0.38) | LMNAMAPTKMT2AALDH1A1TP53 | |
| SCHEMBL12025040 | 0.67 | RXFP1 (0.46) | LMNAMAPTKMT2AALDH1A1NPSR1 | |
| SCHEMBL16453477 | 0.64 | TSHR (0.47) | LMNAMAPTKMT2AALDH1A1TSHR | |
| SCHEMBL17856314 | 0.63 | PARP1 (0.40) | MAPTKMT2AALDH1A1TSHR | |
| SCHEMBL19902996 | 0.62 | KMT2A (0.52) | LMNAMAPTKMT2AALDH1A1NPSR1 | |
| SCHEMBL17724395 | 0.61 | NPSR1 (0.56) | LMNAMAPTKMT2AALDH1A1NPSR1 | |
| SCHEMBL19902931 | 0.61 | HCRTR1 (0.39) | MAPT | |
| SCHEMBL17863848 | 0.60 | NPSR1 (0.40) | KMT2ANPSR1TSHR | |
| SCHEMBL22383524 | 0.60 | GBA1 (0.33) | ALDH1A1TP53TSHR | |
| SCHEMBL22877134 | 0.59 | KDM4E (0.45) | LMNAMAPTKMT2AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287454-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-02-28 | — | — | EP | disclosed |