Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12025040 | 0.82 | RXFP1 (0.46) | LMNAKMT2ARXFP1MAPTADRA1A | |
| SCHEMBL17856314 | 0.73 | PARP1 (0.40) | KMT2ATSHRRXFP1MAPTALDH1A1 | |
| SCHEMBL16453477 | 0.71 | TSHR (0.47) | LMNAKMT2ATSHRMAPTALDH1A1 | |
| SCHEMBL19903067 | 0.71 | LMNA (0.35) | LMNAKMT2ATSHRMAPTALDH1A1 | |
| SCHEMBL19902996 | 0.70 | KMT2A (0.52) | LMNAKMT2AMAPTALDH1A1GAA | |
| SCHEMBL17724395 | 0.70 | NPSR1 (0.56) | LMNAKMT2ATSHRMAPTALDH1A1 | |
| SCHEMBL22877134 | 0.69 | KDM4E (0.45) | LMNAKMT2AMAPTALDH1A1TP53 | |
| SCHEMBL19652346 | 0.68 | NPSR1 (0.38) | KMT2ATSHRGAA | |
| SCHEMBL23018165 | 0.68 | PARP1 (0.36) | RXFP1 | |
| SCHEMBL19902985 | 0.68 | HCRTR2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287454-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-02-28 | — | — | EP | disclosed |