SCHEMBL19903500

SCHEMBL19903500

N#Cc1cc(-n2c3ccccc3c3ccccc32)c(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1-n1c2ccccc2c2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.37
AR P10275 7/20 0.35
CTSS P25774 2/20 0.34
CTSK P43235 1/20 0.34
IMPDH2 P12268 1/20 0.33
PGR P06401 1/20 0.33
CNR2 P34972 1/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
BRD4 O60885 1/20 0.32
TRPA1 O75762 1/20 0.32
SLC22A12 Q96S37 1/20 0.32
GPBAR1 Q8TDU6 1/20 0.32
TACR1 P25103 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19903674 0.94 KIF11 (0.39) KIF11ARCTSSCTSKPGR
SCHEMBL19903672 0.94 KIF11 (0.44) KIF11ARCTSSCTSKCNR2
SCHEMBL19917918 0.93 KIF11 (0.35) KIF11ARCTSSCTSKPGR
SCHEMBL19917926 0.93 ICMT (0.35) KIF11ARPGRKDM4ECYP11B1
SCHEMBL19917925 0.92 AR (0.35) KIF11AR
SCHEMBL19918037 0.92 AR (0.35) KIF11AR
SCHEMBL19917905 0.92 KIF11 (0.33) KIF11ARKDM4E
SCHEMBL19903587 0.92 AR (0.35) KIF11AR
SCHEMBL19918039 0.92 AR (0.35) KIF11AR
SCHEMBL19903627 0.92 KIF11 (0.34) KIF11ARKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4250899-A2 ORGANIC ELECTROLUMINESCENT DEVICE Samsung Display Co., Ltd. (KR) 2023-09-27 EP disclosed
EP-3639308-B1 ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO LTD (KR) 2023-07-26 EP disclosed
US-20210351364-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE SK MATERIALS JNC CO., LTD. (KR) 2021-11-11 US disclosed
US-10439151-B2 Organic molecules, especially for use in organic optoelectronic devices CYNORA GMBH (DE) 2019-10-08 US disclosed
EP-3360945-B1 ORGANIC ELECTROLUMINESCENT DEVICE CYNORA GMBH (DE) 2019-04-24 EP disclosed
EP-3287450-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-03-20 EP disclosed
US-9917270-B1 Organic electroluminescent device having an exciton quenching layer CYNORA GMBH (DE) 2018-03-13 US disclosed
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287450-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10439151-B2 Organic molecules, especially for use in organic optoelectronic devices OR10J3, ORC3, AOC3 KIF11 3253/4885AR 4190/4885CTSS 4248/4885
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, ORC3, AOC3 KIF11 3316/4885AR 4212/4885CTSS 4073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.