SCHEMBL19903579

SCHEMBL19903579

Cc1ccc2c(c1)c1cc(C)ccc1n2-c1cc(C#N)c(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1-n1c2ccc(C)cc2c2cc(C)ccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 5/20 0.36
SMN1; SMN2 Q16637 2/20 0.34
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.34
HTT P42858 1/20 0.34
NCOA1 Q15788 1/20 0.34
HIF1A Q16665 1/20 0.34
NCOA3 Q9Y6Q9 1/20 0.34
TSHR P16473 1/20 0.34
XDH P47989 2/20 0.33
HTR6 P50406 2/20 0.33
HRH1 P35367 1/20 0.33
KIF11 P52732 1/20 0.33
PIK3CA P42336 1/20 0.32
PIK3CB P42338 1/20 0.32
PIK3CG P48736 1/20 0.32
CTSS P25774 1/20 0.32
CTSK P43235 1/20 0.32
PGR P06401 1/20 0.32
MAOA P21397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19912355 0.95 AR (0.36) ARSMN1; SMN2LMNAPOLBHTT
SCHEMBL19903576 0.94 AR (0.34) ARSMN1; SMN2LMNAPOLBHTT
SCHEMBL20617048 0.94 RXRA (0.37) ARSMN1; SMN2LMNAPOLBHTT
SCHEMBL19917810 0.92 AR (0.45) ARSMN1; SMN2TSHRXDHKIF11
SCHEMBL19903604 0.92 AR (0.36) ARSMN1; SMN2LMNAPOLBHTT
SCHEMBL19903578 0.91 AR (0.36) ARSMN1; SMN2LMNAPOLBHTT
SCHEMBL19912356 0.90 AR (0.35) ARSMN1; SMN2LMNAPOLBHTT
SCHEMBL20617041 0.90 RXRA (0.34) ARSMN1; SMN2HTTTSHRXDH
SCHEMBL21440728 0.89 AR (0.48) ARXDHCTSSPGRKDM4E
SCHEMBL19903507 0.89 TSHR (0.36) ARSMN1; SMN2TSHRXDHKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3360945-B1 ORGANIC ELECTROLUMINESCENT DEVICE CYNORA GMBH (DE) 2019-04-24 EP disclosed
EP-3287450-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-03-20 EP disclosed
EP-3287450-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed