SCHEMBL19917810

SCHEMBL19917810

Cc1ccc(-c2ccc3c(c2)c2cc(-c4ccc(C)cc4)ccc2n3-c2cc(C#N)c(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)cc2-n2c3ccc(-c4ccc(C)cc4)cc3c3cc(-c4ccc(C)cc4)ccc32)cc1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AR P10275 6/20 0.45
MAOA P21397 3/20 0.34
MAOB P27338 3/20 0.34
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34
XDH P47989 2/20 0.33
ICMT O60725 2/20 0.33
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PGR P06401 1/20 0.33
RXRA P19793 1/20 0.32
RXRG P48443 1/20 0.32
KIF11 P52732 1/20 0.32
ERBB2 P04626 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19917814 0.95 AR (0.41) ARMAOAMAOBCYP11B1CYP11B2
SCHEMBL22822157 0.95 AR (0.43) ARMAOAMAOBCYP11B1CYP11B2
SCHEMBL19917943 0.92 AR (0.37) ARCYP11B1CYP11B2XDHICMT
SCHEMBL19917917 0.92 AR (0.44) ARMAOAMAOBCYP11B1CYP11B2
SCHEMBL19903579 0.92 AR (0.36) ARMAOAMAOBCYP11B1CYP11B2
SCHEMBL19917914 0.92 CYP11B1 (0.37) ARCYP11B1CYP11B2XDHICMT
SCHEMBL21440728 0.90 AR (0.48) ARCYP11B1CYP11B2XDHICMT
SCHEMBL22822156 0.90 AR (0.39) ARXDHICMTSMN1; SMN2RXRA
SCHEMBL19903476 0.90 KIF11 (0.43) ARCYP11B1CYP11B2PGRRXRA
SCHEMBL19903479 0.90 XDH (0.36) ARCYP11B1CYP11B2XDHICMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10439151-B2 Organic molecules, especially for use in organic optoelectronic devices CYNORA GMBH (DE) 2019-10-08 US disclosed
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10439151-B2 Organic molecules, especially for use in organic optoelectronic devices OR10J3, ORC3, AOC3 AR 4190/4885MAOA 455/4885MAOB 393/4885
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, ORC3, AOC3 AR 4212/4885MAOA 452/4885MAOB 361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.