SCHEMBL19903765

SCHEMBL19903765

CC(C)(C)OC(=O)NCC(=O)NCCOCCOCCOCCOCCC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
GAA P10253 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
IDO1 P14902 1/20 0.37
SUCNR1 Q9BXA5 2/20 0.36
CA12 O43570 3/20 0.36
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA9 Q16790 3/20 0.36
NPFFR1 Q9GZQ6 1/20 0.35
NPFFR2 Q9Y5X5 1/20 0.35
BCHE P06276 1/20 0.35
CNR2 P34972 1/20 0.35
PLK1 P53350 2/20 0.35
ADRB2 P07550 1/20 0.34
HTR1A P08908 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23418049 0.96 MEN1 (0.38) MEN1KMT2AGAATDP1MAOA
SCHEMBL29467663 0.90 MEN1 (0.44) MEN1KMT2AGAATDP1MAOA
SCHEMBL12238318 0.90 MEN1 (0.49) MEN1KMT2AGAATDP1MAOA
SCHEMBL22939187 0.90 MEN1 (0.49) MEN1KMT2AGAATDP1MAOA
SCHEMBL436333 0.90 MEN1 (0.49) MEN1KMT2AGAATDP1MAOA
SCHEMBL25257785 0.90 MEN1 (0.49) MEN1KMT2AGAATDP1MAOA
SCHEMBL12092148 0.90 MEN1 (0.49) MEN1KMT2AGAATDP1MAOA
SCHEMBL14671684 0.90 MEN1 (0.49) MEN1KMT2AGAATDP1MAOA
SCHEMBL13699509 0.90 MEN1 (0.49) MEN1KMT2AGAATDP1MAOA
SCHEMBL7263734 0.90 MEN1 (0.49) MEN1KMT2AGAATDP1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2949665-B1 GLYCOSYLATION ATRIAL NATRIURETIC PEPTIDE DAIICHI SANKYO CO LTD (JP) 2018-02-28 EP disclosed